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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC12
All Species:
16.97
Human Site:
S253
Identified Species:
37.33
UniProt:
Q9H892
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H892
NP_060338.3
705
78738
S253
K
N
L
L
E
T
L
S
K
P
D
Q
I
P
L
Chimpanzee
Pan troglodytes
XP_508759
732
81550
S253
K
N
L
L
E
T
L
S
K
P
D
Q
I
P
L
Rhesus Macaque
Macaca mulatta
XP_001084630
705
78442
S253
K
N
L
L
E
T
L
S
K
P
D
Q
I
P
L
Dog
Lupus familis
XP_536570
689
77080
C237
K
N
L
L
E
T
L
C
K
P
D
Q
N
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BW49
704
78735
S252
K
N
L
L
E
T
L
S
K
P
G
Q
T
P
L
Rat
Rattus norvegicus
NP_001004246
704
78845
S252
R
N
L
L
E
T
L
S
K
P
G
Q
T
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521579
596
64809
V188
S
I
I
N
D
N
K
V
I
K
R
C
L
S
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NU95
660
75087
L211
A
R
R
G
A
A
R
L
A
L
K
N
L
Q
G
Zebra Danio
Brachydanio rerio
XP_692245
1008
111628
I252
G
T
G
Q
A
T
N
I
A
D
L
L
K
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794332
573
63704
Q165
E
S
G
D
M
H
S
Q
T
M
T
D
V
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12118
346
37200
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
95.1
76.3
N.A.
75
77
N.A.
49.2
N.A.
20.7
26.8
N.A.
N.A.
N.A.
N.A.
27.8
Protein Similarity:
100
94.4
97.8
87.5
N.A.
88.6
89.6
N.A.
62.7
N.A.
41.4
44.8
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Identity:
100
100
100
86.6
N.A.
86.6
80
N.A.
0
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
20
N.A.
6.6
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
31.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
19
10
0
0
19
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
10
10
0
0
0
0
10
37
10
0
0
0
% D
% Glu:
10
0
0
0
55
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
19
10
0
0
0
0
0
0
19
0
0
0
10
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
0
0
0
10
10
0
0
0
28
0
0
% I
% Lys:
46
0
0
0
0
0
10
0
55
10
10
0
10
10
0
% K
% Leu:
0
0
55
55
0
0
55
10
0
10
10
10
19
10
64
% L
% Met:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
55
0
10
0
10
10
0
0
0
0
10
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
55
0
0
0
55
0
% P
% Gln:
0
0
0
10
0
0
0
10
0
0
0
55
0
10
0
% Q
% Arg:
10
10
10
0
0
0
10
0
0
0
10
0
0
0
0
% R
% Ser:
10
10
0
0
0
0
10
46
0
0
0
0
0
10
10
% S
% Thr:
0
10
0
0
0
64
0
0
10
0
10
0
19
0
10
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _