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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC12
All Species:
21.82
Human Site:
S292
Identified Species:
48
UniProt:
Q9H892
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H892
NP_060338.3
705
78738
S292
H
N
G
F
S
I
I
S
D
N
E
V
I
R
R
Chimpanzee
Pan troglodytes
XP_508759
732
81550
S292
H
N
G
F
S
I
I
S
D
N
E
V
I
R
R
Rhesus Macaque
Macaca mulatta
XP_001084630
705
78442
S292
H
D
G
F
S
I
I
S
D
N
E
V
I
R
R
Dog
Lupus familis
XP_536570
689
77080
S276
H
N
G
F
S
I
I
S
E
N
E
V
V
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BW49
704
78735
S291
Y
G
G
F
S
T
I
S
D
H
E
V
I
R
R
Rat
Rattus norvegicus
NP_001004246
704
78845
N291
Y
G
G
F
S
I
I
N
D
H
E
V
I
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521579
596
64809
L227
N
E
V
N
Q
H
R
L
V
T
H
P
G
L
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NU95
660
75087
S250
I
N
Q
E
L
Y
S
S
A
S
D
V
Q
E
N
Zebra Danio
Brachydanio rerio
XP_692245
1008
111628
T291
A
S
H
R
I
Q
K
T
Q
M
R
W
I
Y
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794332
573
63704
S204
N
S
R
A
V
V
E
S
E
D
F
A
S
T
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12118
346
37200
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
95.1
76.3
N.A.
75
77
N.A.
49.2
N.A.
20.7
26.8
N.A.
N.A.
N.A.
N.A.
27.8
Protein Similarity:
100
94.4
97.8
87.5
N.A.
88.6
89.6
N.A.
62.7
N.A.
41.4
44.8
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Identity:
100
100
93.3
86.6
N.A.
73.3
66.6
N.A.
0
N.A.
20
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
6.6
N.A.
33.3
20
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
31.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
0
0
0
10
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
46
10
10
0
0
0
0
% D
% Glu:
0
10
0
10
0
0
10
0
19
0
55
0
0
10
0
% E
% Phe:
0
0
0
55
0
0
0
0
0
0
10
0
0
0
10
% F
% Gly:
0
19
55
0
0
0
0
0
0
0
0
0
10
0
10
% G
% His:
37
0
10
0
0
10
0
0
0
19
10
0
0
0
0
% H
% Ile:
10
0
0
0
10
46
55
0
0
0
0
0
55
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
0
10
0
0
10
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
19
37
0
10
0
0
0
10
0
37
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
10
0
10
10
0
0
10
0
0
0
10
0
0
% Q
% Arg:
0
0
10
10
0
0
10
0
0
0
10
0
0
46
55
% R
% Ser:
0
19
0
0
55
0
10
64
0
10
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
10
0
10
0
10
0
0
0
10
0
% T
% Val:
0
0
10
0
10
10
0
0
10
0
0
64
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
19
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _