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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC12
All Species:
12.12
Human Site:
S372
Identified Species:
26.67
UniProt:
Q9H892
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H892
NP_060338.3
705
78738
S372
L
H
L
A
Q
T
E
S
G
R
S
L
I
I
N
Chimpanzee
Pan troglodytes
XP_508759
732
81550
S372
L
Q
L
A
Q
T
E
S
G
R
S
L
I
I
N
Rhesus Macaque
Macaca mulatta
XP_001084630
705
78442
S372
L
Q
L
A
Q
T
E
S
G
R
S
L
I
I
S
Dog
Lupus familis
XP_536570
689
77080
Y356
L
Q
L
T
Q
T
D
Y
G
R
S
L
V
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BW49
704
78735
N371
L
Q
L
T
Q
T
E
N
G
R
N
Q
V
I
K
Rat
Rattus norvegicus
NP_001004246
704
78845
N371
L
Q
L
T
Q
T
D
N
G
R
N
Q
V
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521579
596
64809
R298
V
R
A
G
E
A
M
R
L
L
T
D
L
A
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NU95
660
75087
A325
A
L
L
P
A
N
R
A
M
A
Y
L
K
I
Q
Zebra Danio
Brachydanio rerio
XP_692245
1008
111628
I363
T
Q
H
G
R
E
L
I
I
H
N
L
D
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794332
573
63704
N275
V
E
A
A
K
V
L
N
N
L
A
L
E
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12118
346
37200
R48
S
E
A
F
G
F
E
R
E
A
V
S
G
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
95.1
76.3
N.A.
75
77
N.A.
49.2
N.A.
20.7
26.8
N.A.
N.A.
N.A.
N.A.
27.8
Protein Similarity:
100
94.4
97.8
87.5
N.A.
88.6
89.6
N.A.
62.7
N.A.
41.4
44.8
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Identity:
100
93.3
86.6
60
N.A.
53.3
46.6
N.A.
0
N.A.
20
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
93.3
80
N.A.
73.3
73.3
N.A.
26.6
N.A.
26.6
20
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
31.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
28
37
10
10
0
10
0
19
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
19
0
0
0
0
10
10
0
0
% D
% Glu:
0
19
0
0
10
10
46
0
10
0
0
0
10
0
0
% E
% Phe:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
19
10
0
0
0
55
0
0
0
10
0
0
% G
% His:
0
10
10
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
10
0
0
0
28
73
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
28
% K
% Leu:
55
10
64
0
0
0
19
0
10
19
0
64
10
0
19
% L
% Met:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
28
10
0
28
0
0
0
19
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
55
0
0
55
0
0
0
0
0
0
19
0
0
19
% Q
% Arg:
0
10
0
0
10
0
10
19
0
55
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
28
0
0
37
10
0
19
19
% S
% Thr:
10
0
0
28
0
55
0
0
0
0
10
0
0
0
0
% T
% Val:
19
0
0
0
0
10
0
0
0
0
10
0
28
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _