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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC12
All Species:
22.42
Human Site:
S459
Identified Species:
49.33
UniProt:
Q9H892
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H892
NP_060338.3
705
78738
S459
I
A
I
M
G
N
L
S
A
E
P
T
T
R
R
Chimpanzee
Pan troglodytes
XP_508759
732
81550
S459
I
T
V
M
G
N
L
S
A
E
P
T
T
R
R
Rhesus Macaque
Macaca mulatta
XP_001084630
705
78442
S459
I
A
I
M
G
N
L
S
A
E
P
A
T
R
R
Dog
Lupus familis
XP_536570
689
77080
S443
I
A
L
M
G
N
L
S
A
E
A
A
V
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BW49
704
78735
S458
I
A
L
L
G
N
I
S
A
E
P
T
A
R
K
Rat
Rattus norvegicus
NP_001004246
704
78845
S458
I
A
L
M
G
N
I
S
A
E
P
T
A
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521579
596
64809
W376
C
L
E
F
L
L
G
W
E
E
D
L
V
P
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NU95
660
75087
N409
I
E
K
D
R
N
G
N
K
D
S
N
Q
R
K
Zebra Danio
Brachydanio rerio
XP_692245
1008
111628
A444
I
S
V
I
G
T
I
A
Q
D
D
A
I
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794332
573
63704
T353
I
K
V
L
K
F
H
T
K
H
L
D
K
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12118
346
37200
T126
E
L
A
I
N
K
Y
T
E
A
I
K
V
L
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
95.1
76.3
N.A.
75
77
N.A.
49.2
N.A.
20.7
26.8
N.A.
N.A.
N.A.
N.A.
27.8
Protein Similarity:
100
94.4
97.8
87.5
N.A.
88.6
89.6
N.A.
62.7
N.A.
41.4
44.8
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Identity:
100
86.6
93.3
73.3
N.A.
66.6
80
N.A.
6.6
N.A.
20
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
80
N.A.
93.3
93.3
N.A.
6.6
N.A.
40
60
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
31.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
46
10
0
0
0
0
10
55
10
10
28
19
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
19
19
10
0
0
0
% D
% Glu:
10
10
10
0
0
0
0
0
19
64
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
64
0
19
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% H
% Ile:
82
0
19
19
0
0
28
0
0
0
10
0
10
0
0
% I
% Lys:
0
10
10
0
10
10
0
0
19
0
0
10
10
0
28
% K
% Leu:
0
19
28
19
10
10
37
0
0
0
10
10
0
10
0
% L
% Met:
0
0
0
46
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
64
0
10
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
46
0
0
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
0
0
0
64
46
% R
% Ser:
0
10
0
0
0
0
0
55
0
0
10
0
0
19
10
% S
% Thr:
0
10
0
0
0
10
0
19
0
0
0
37
28
0
0
% T
% Val:
0
0
28
0
0
0
0
0
0
0
0
0
28
0
10
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _