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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC12 All Species: 10.3
Human Site: T438 Identified Species: 22.67
UniProt: Q9H892 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.4
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H892 NP_060338.3 705 78738 T438 A L T G V L K T D P K V S S S
Chimpanzee Pan troglodytes XP_508759 732 81550 T438 A L T G V L K T D P K V S S S
Rhesus Macaque Macaca mulatta XP_001084630 705 78442 T438 A V T G V L K T D P K V S S S
Dog Lupus familis XP_536570 689 77080 R422 V L T G V L E R D P M V T S P
Cat Felis silvestris
Mouse Mus musculus Q8BW49 704 78735 R437 A L T G A L N R E P K I T S P
Rat Rattus norvegicus NP_001004246 704 78845 R437 A L T G A L K R E P K L T S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521579 596 64809 I355 N L S A D V T I R S Q L A A C
Chicken Gallus gallus
Frog Xenopus laevis Q6NU95 660 75087 A388 L D P G N K Q A V L E L A K I
Zebra Danio Brachydanio rerio XP_692245 1008 111628 S423 L P L E D L L S N T T T A D P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794332 573 63704 R332 M A H D P V I R K E I A S R K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12118 346 37200 L105 T K A K A E D L K M Q G N K A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93 95.1 76.3 N.A. 75 77 N.A. 49.2 N.A. 20.7 26.8 N.A. N.A. N.A. N.A. 27.8
Protein Similarity: 100 94.4 97.8 87.5 N.A. 88.6 89.6 N.A. 62.7 N.A. 41.4 44.8 N.A. N.A. N.A. N.A. 46.6
P-Site Identity: 100 100 93.3 60 N.A. 53.3 60 N.A. 6.6 N.A. 6.6 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 73.3 N.A. 73.3 80 N.A. 46.6 N.A. 33.3 26.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 31.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 46 10 10 10 28 0 0 10 0 0 0 10 28 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 10 0 10 19 0 10 0 37 0 0 0 0 10 0 % D
% Glu: 0 0 0 10 0 10 10 0 19 10 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 64 0 0 0 0 0 0 0 10 0 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 10 0 0 10 10 0 0 10 % I
% Lys: 0 10 0 10 0 10 37 0 19 0 46 0 0 19 10 % K
% Leu: 19 55 10 0 0 64 10 10 0 10 0 28 0 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % M
% Asn: 10 0 0 0 10 0 10 0 10 0 0 0 10 0 0 % N
% Pro: 0 10 10 0 10 0 0 0 0 55 0 0 0 0 37 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 19 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 37 10 0 0 0 0 10 0 % R
% Ser: 0 0 10 0 0 0 0 10 0 10 0 0 37 55 28 % S
% Thr: 10 0 55 0 0 0 10 28 0 10 10 10 28 0 0 % T
% Val: 10 10 0 0 37 19 0 0 10 0 0 37 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _