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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC12 All Species: 12.42
Human Site: T463 Identified Species: 27.33
UniProt: Q9H892 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H892 NP_060338.3 705 78738 T463 G N L S A E P T T R R H M A A
Chimpanzee Pan troglodytes XP_508759 732 81550 T463 G N L S A E P T T R R H M A A
Rhesus Macaque Macaca mulatta XP_001084630 705 78442 A463 G N L S A E P A T R R H M A A
Dog Lupus familis XP_536570 689 77080 A447 G N L S A E A A V R R Q M F A
Cat Felis silvestris
Mouse Mus musculus Q8BW49 704 78735 T462 G N I S A E P T A R K H M I A
Rat Rattus norvegicus NP_001004246 704 78845 T462 G N I S A E P T A R R H M L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521579 596 64809 L380 L L G W E E D L V P V R G T V
Chicken Gallus gallus
Frog Xenopus laevis Q6NU95 660 75087 N413 R N G N K D S N Q R K L I N T
Zebra Danio Brachydanio rerio XP_692245 1008 111628 A448 G T I A Q D D A I S K N L A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794332 573 63704 D357 K F H T K H L D K S S S R E M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12118 346 37200 K130 N K Y T E A I K V L P T N A I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93 95.1 76.3 N.A. 75 77 N.A. 49.2 N.A. 20.7 26.8 N.A. N.A. N.A. N.A. 27.8
Protein Similarity: 100 94.4 97.8 87.5 N.A. 88.6 89.6 N.A. 62.7 N.A. 41.4 44.8 N.A. N.A. N.A. N.A. 46.6
P-Site Identity: 100 100 93.3 66.6 N.A. 73.3 80 N.A. 6.6 N.A. 13.3 13.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 93.3 66.6 N.A. 86.6 86.6 N.A. 6.6 N.A. 40 53.3 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 31.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 55 10 10 28 19 0 0 0 0 46 55 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 19 19 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 19 64 0 0 0 0 0 0 0 10 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 64 0 19 0 0 0 0 0 0 0 0 0 10 0 10 % G
% His: 0 0 10 0 0 10 0 0 0 0 0 46 0 0 0 % H
% Ile: 0 0 28 0 0 0 10 0 10 0 0 0 10 10 10 % I
% Lys: 10 10 0 0 19 0 0 10 10 0 28 0 0 0 0 % K
% Leu: 10 10 37 0 0 0 10 10 0 10 0 10 10 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 55 0 10 % M
% Asn: 10 64 0 10 0 0 0 10 0 0 0 10 10 10 0 % N
% Pro: 0 0 0 0 0 0 46 0 0 10 10 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 10 0 0 10 0 0 0 % Q
% Arg: 10 0 0 0 0 0 0 0 0 64 46 10 10 0 0 % R
% Ser: 0 0 0 55 0 0 10 0 0 19 10 10 0 0 0 % S
% Thr: 0 10 0 19 0 0 0 37 28 0 0 10 0 10 10 % T
% Val: 0 0 0 0 0 0 0 0 28 0 10 0 0 0 10 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _