Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX31 All Species: 12.42
Human Site: S275 Identified Species: 18.22
UniProt: Q9H8H2 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H8H2 NP_073616.6 851 94087 S275 G R D A L V R S Q T G S G K T
Chimpanzee Pan troglodytes XP_001168526 851 93934 S275 G R D A L V R S Q T G S G K T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537810 710 79297 P186 P Y A L V L V P T R E L A L Q
Cat Felis silvestris
Mouse Mus musculus Q8K363 660 74162 E136 A K T E E S A E A C E E P E D
Rat Rattus norvegicus NP_001101294 682 76371 Y158 G S G K T L A Y C I P V V Q S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511356 653 72400 S129 H L V S T I T S V L K M S S M
Chicken Gallus gallus XP_425332 710 80182 I186 L Q G M Q S K I Q R S D G P Y
Frog Xenopus laevis NP_001088376 554 61485 G30 V L V R S Q T G S G K T M A Y
Zebra Danio Brachydanio rerio XP_683832 739 82077 Q215 A Y G I P M V Q F L Q A I Q P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q86B47 975 107950 S372 G K D V L V R S Q T G S G K T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784918 690 76682 P166 T V Q Q R A I P T L L H G Q D
Poplar Tree Populus trichocarpa XP_002325490 594 67215 T70 L V N A A T G T G K T V A Y L
Maize Zea mays NP_001169005 599 67314 T75 L V K A A T G T G K T L A Y L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q7XJN0 609 68195 L85 T G K T I A Y L A P L I H H L
Baker's Yeast Sacchar. cerevisiae P36120 742 83290 R218 N M D T H V D R T S G A F A L
Red Bread Mold Neurospora crassa Q7S873 814 88489 L260 V L R C A P W L V C T T V I G
Conservation
Percent
Protein Identity: 100 98.5 N.A. 69.2 N.A. 29.8 64.9 N.A. 58.5 56.8 42.7 49.4 N.A. 31.3 N.A. N.A. 40.7
Protein Similarity: 100 99.2 N.A. 73.9 N.A. 45.8 71 N.A. 66.2 67.9 51.9 63.2 N.A. 50.1 N.A. N.A. 53.2
P-Site Identity: 100 100 N.A. 0 N.A. 0 6.6 N.A. 6.6 13.3 0 0 N.A. 86.6 N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. 13.3 N.A. 13.3 26.6 N.A. 20 26.6 6.6 20 N.A. 93.3 N.A. N.A. 13.3
Percent
Protein Identity: 23.5 22.8 N.A. 24.9 25.2 25.5
Protein Similarity: 39.4 38.3 N.A. 39.2 46.3 42.8
P-Site Identity: 6.6 6.6 N.A. 0 20 0
P-Site Similarity: 20 13.3 N.A. 6.6 33.3 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 7 25 19 13 13 0 13 0 0 13 19 13 0 % A
% Cys: 0 0 0 7 0 0 0 0 7 13 0 0 0 0 0 % C
% Asp: 0 0 25 0 0 0 7 0 0 0 0 7 0 0 13 % D
% Glu: 0 0 0 7 7 0 0 7 0 0 13 7 0 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 7 0 0 0 7 0 0 % F
% Gly: 25 7 19 0 0 0 13 7 13 7 25 0 32 0 7 % G
% His: 7 0 0 0 7 0 0 0 0 0 0 7 7 7 0 % H
% Ile: 0 0 0 7 7 7 7 7 0 7 0 7 7 7 0 % I
% Lys: 0 13 13 7 0 0 7 0 0 13 13 0 0 19 0 % K
% Leu: 19 19 0 7 19 13 0 13 0 19 13 13 0 7 25 % L
% Met: 0 7 0 7 0 7 0 0 0 0 0 7 7 0 7 % M
% Asn: 7 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 7 0 0 0 7 7 0 13 0 7 7 0 7 7 7 % P
% Gln: 0 7 7 7 7 7 0 7 25 0 7 0 0 19 7 % Q
% Arg: 0 13 7 7 7 0 19 7 0 13 0 0 0 0 0 % R
% Ser: 0 7 0 7 7 13 0 25 7 7 7 19 7 7 7 % S
% Thr: 13 0 7 13 13 13 13 13 19 19 19 13 0 0 19 % T
% Val: 13 19 13 7 7 25 13 0 13 0 0 13 13 0 0 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 0 13 0 0 0 0 7 7 0 0 0 0 0 13 13 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _