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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL7A
All Species:
31.21
Human Site:
S110
Identified Species:
68.67
UniProt:
Q9H8H3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H8H3
NP_054752.3
244
28319
S110
F
E
K
F
L
I
K
S
I
A
E
N
R
H
L
Chimpanzee
Pan troglodytes
XP_001152216
244
28325
S110
F
E
K
F
L
I
K
S
I
A
E
N
R
H
L
Rhesus Macaque
Macaca mulatta
XP_001083584
244
28087
S110
F
E
K
F
L
I
K
S
I
A
E
N
R
H
L
Dog
Lupus familis
XP_531623
244
27636
S110
F
E
K
F
L
T
K
S
M
A
E
N
R
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DD20
244
28030
S110
F
E
K
F
L
T
K
S
M
A
E
N
R
H
L
Rat
Rattus norvegicus
Q562C4
244
27885
S110
F
E
K
F
L
T
K
S
M
A
E
N
R
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521711
116
13303
Chicken
Gallus gallus
XP_424479
246
27900
S112
F
Q
Q
G
L
S
R
S
M
S
K
N
Q
H
I
Frog
Xenopus laevis
NP_001088746
244
27427
S110
F
Q
S
F
L
G
R
S
L
A
E
S
Q
H
V
Zebra Danio
Brachydanio rerio
XP_697545
242
27759
E117
I
E
K
N
E
H
L
E
Y
D
N
F
I
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002312254
317
34394
S184
M
E
K
F
A
Q
E
S
A
V
A
A
G
L
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
92.6
56.5
N.A.
58.2
56.5
N.A.
32.7
60.5
58.6
52.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.7
95.4
72.9
N.A.
75
75.4
N.A.
40.9
76
77.8
70.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
0
33.3
46.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
0
86.6
86.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
31.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
45.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
10
64
10
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
73
0
0
10
0
10
10
0
0
64
0
0
0
0
% E
% Phe:
73
0
0
73
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
10
0
10
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
73
0
% H
% Ile:
10
0
0
0
0
28
0
0
28
0
0
0
10
0
10
% I
% Lys:
0
0
73
0
0
0
55
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
73
0
10
0
10
0
0
0
0
10
55
% L
% Met:
10
0
0
0
0
0
0
0
37
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
10
64
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
19
10
0
0
10
0
0
0
0
0
0
19
0
0
% Q
% Arg:
0
0
0
0
0
0
19
0
0
0
0
0
55
0
0
% R
% Ser:
0
0
10
0
0
10
0
82
0
10
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
28
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _