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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL7A
All Species:
30
Human Site:
S218
Identified Species:
66
UniProt:
Q9H8H3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H8H3
NP_054752.3
244
28319
S218
A
L
E
R
A
S
F
S
K
L
K
L
Q
H
I
Chimpanzee
Pan troglodytes
XP_001152216
244
28325
S218
A
L
E
R
A
S
F
S
K
L
K
L
Q
H
I
Rhesus Macaque
Macaca mulatta
XP_001083584
244
28087
S218
T
L
E
R
A
G
F
S
K
L
K
L
Q
H
I
Dog
Lupus familis
XP_531623
244
27636
S218
D
L
E
S
A
Q
F
S
H
L
Q
M
E
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9DD20
244
28030
S218
D
I
E
R
A
Q
F
S
E
V
Q
L
E
W
Q
Rat
Rattus norvegicus
Q562C4
244
27885
S218
D
I
E
K
A
Q
F
S
E
V
Q
L
E
W
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521711
116
13303
R91
L
E
R
A
G
F
S
R
L
Q
L
Q
R
M
Q
Chicken
Gallus gallus
XP_424479
246
27900
S220
D
L
E
E
A
N
F
S
E
L
K
L
Q
H
I
Frog
Xenopus laevis
NP_001088746
244
27427
S218
Y
L
E
S
G
K
F
S
N
V
K
L
R
H
I
Zebra Danio
Brachydanio rerio
XP_697545
242
27759
S217
H
I
E
A
A
G
F
S
D
V
K
L
H
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002312254
317
34394
S292
E
I
L
K
A
G
F
S
S
V
D
L
S
M
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
92.6
56.5
N.A.
58.2
56.5
N.A.
32.7
60.5
58.6
52.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.7
95.4
72.9
N.A.
75
75.4
N.A.
40.9
76
77.8
70.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
40
N.A.
40
33.3
N.A.
0
73.3
53.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
60
N.A.
73.3
73.3
N.A.
6.6
86.6
66.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
31.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
45.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
19
82
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
37
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% D
% Glu:
10
10
82
10
0
0
0
0
28
0
0
0
28
0
0
% E
% Phe:
0
0
0
0
0
10
91
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
19
28
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
10
0
0
0
10
55
0
% H
% Ile:
0
37
0
0
0
0
0
0
0
0
0
0
0
0
55
% I
% Lys:
0
0
0
19
0
10
0
0
28
0
55
0
0
0
0
% K
% Leu:
10
55
10
0
0
0
0
0
10
46
10
82
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
19
0
% M
% Asn:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
28
0
0
0
10
28
10
37
10
37
% Q
% Arg:
0
0
10
37
0
0
0
10
0
0
0
0
19
0
0
% R
% Ser:
0
0
0
19
0
19
10
91
10
0
0
0
10
0
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
46
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _