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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METTL7A All Species: 15.76
Human Site: S60 Identified Species: 34.67
UniProt: Q9H8H3 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H8H3 NP_054752.3 244 28319 S60 S K K R E L F S N L Q E F A G
Chimpanzee Pan troglodytes XP_001152216 244 28325 S60 S K K R E L F S N L Q E F A G
Rhesus Macaque Macaca mulatta XP_001083584 244 28087 G60 S K K R E L F G N L Q E F A G
Dog Lupus familis XP_531623 244 27636 G60 R K K Q E L F G Q I N R L T G
Cat Felis silvestris
Mouse Mus musculus Q9DD20 244 28030 S60 S K K R E L F S Q I K D L K G
Rat Rattus norvegicus Q562C4 244 27885 S60 S K K R E L F S Q I K D L K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521711 116 13303
Chicken Gallus gallus XP_424479 246 27900 R62 K Q K Q E L F R N L P D F T G
Frog Xenopus laevis NP_001088746 244 27427 S60 D E K R K L F S N L S D F A G
Zebra Danio Brachydanio rerio XP_697545 242 27759 P67 N L E R F Q P P E G S L R I L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002312254 317 34394 Q134 E V A V Y K T Q L F T N L R G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 92.6 56.5 N.A. 58.2 56.5 N.A. 32.7 60.5 58.6 52.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.7 95.4 72.9 N.A. 75 75.4 N.A. 40.9 76 77.8 70.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 40 N.A. 60 60 N.A. 0 53.3 66.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 53.3 N.A. 80 80 N.A. 0 73.3 86.6 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 31.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 45.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 6.6 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 0 0 0 0 0 37 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 37 0 0 0 % D
% Glu: 10 10 10 0 64 0 0 0 10 0 0 28 0 0 0 % E
% Phe: 0 0 0 0 10 0 73 0 0 10 0 0 46 0 0 % F
% Gly: 0 0 0 0 0 0 0 19 0 10 0 0 0 0 82 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 28 0 0 0 10 0 % I
% Lys: 10 55 73 0 10 10 0 0 0 0 19 0 0 19 0 % K
% Leu: 0 10 0 0 0 73 0 0 10 46 0 10 37 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 46 0 10 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 10 10 0 0 10 0 0 0 0 % P
% Gln: 0 10 0 19 0 10 0 10 28 0 28 0 0 0 0 % Q
% Arg: 10 0 0 64 0 0 0 10 0 0 0 10 10 10 0 % R
% Ser: 46 0 0 0 0 0 0 46 0 0 19 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 10 0 0 0 10 0 0 19 0 % T
% Val: 0 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _