KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CNNM2
All Species:
15.15
Human Site:
T589
Identified Species:
41.67
UniProt:
Q9H8M5
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H8M5
NP_060119.3
875
96623
T589
L
D
E
T
D
L
Y
T
D
N
R
T
K
K
K
Chimpanzee
Pan troglodytes
XP_001171907
852
94222
I577
E
D
V
I
E
E
I
I
K
S
E
I
L
D
E
Rhesus Macaque
Macaca mulatta
XP_001098651
560
62894
I287
R
T
K
T
V
E
D
I
M
T
Q
L
Q
D
C
Dog
Lupus familis
XP_543996
875
96506
T589
L
D
E
T
D
L
Y
T
D
N
R
T
K
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3TWN3
875
96626
T589
L
D
E
T
D
L
Y
T
D
N
R
T
K
K
K
Rat
Rattus norvegicus
Q5U2P1
875
96591
T589
L
D
E
T
D
L
Y
T
D
N
R
T
K
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511867
631
70896
R358
K
K
V
A
H
R
E
R
K
Q
D
F
S
A
F
Chicken
Gallus gallus
XP_426532
596
66901
R323
K
K
V
A
H
R
D
R
K
Q
D
F
S
A
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922805
816
91583
T536
D
L
Y
T
D
N
K
T
K
K
K
I
T
H
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
49.3
98.8
N.A.
97.7
97.7
N.A.
69.1
65.3
N.A.
76.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.3
56.9
99.3
N.A.
98.8
98.9
N.A.
70.6
67.1
N.A.
84.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
100
N.A.
100
100
N.A.
0
0
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
26.6
100
N.A.
100
100
N.A.
0
0
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
23
0
0
0
0
0
0
0
0
0
23
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% C
% Asp:
12
56
0
0
56
0
23
0
45
0
23
0
0
23
0
% D
% Glu:
12
0
45
0
12
23
12
0
0
0
12
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
23
0
0
23
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
23
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
0
0
0
12
0
0
12
23
0
0
0
23
0
0
0
% I
% Lys:
23
23
12
0
0
0
12
0
45
12
12
0
45
45
45
% K
% Leu:
45
12
0
0
0
45
0
0
0
0
0
12
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
0
0
0
45
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
23
12
0
12
0
0
% Q
% Arg:
12
0
0
0
0
23
0
23
0
0
45
0
0
0
12
% R
% Ser:
0
0
0
0
0
0
0
0
0
12
0
0
23
0
0
% S
% Thr:
0
12
0
67
0
0
0
56
0
12
0
45
12
0
0
% T
% Val:
0
0
34
0
12
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
0
45
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _