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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM188A All Species: 16.06
Human Site: S22 Identified Species: 32.12
UniProt: Q9H8M7 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H8M7 NP_079224.1 445 49725 S22 T K S S P G L S D T I F C R W
Chimpanzee Pan troglodytes XP_001149628 445 49688 S22 T K S S P G L S D T I F C R W
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544246 480 53561 R57 T V W G L E P R R S C L K V T
Cat Felis silvestris
Mouse Mus musculus Q9CV28 444 49594 S22 T K S S P G L S D T I F C R W
Rat Rattus norvegicus NP_001099592 444 49484 S22 T K S S P G L S D T I F C R W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508622 447 50159 S22 N Q S S P G F S G H I P C P H
Chicken Gallus gallus XP_418629 445 50220 A23 K T G P R G L A D T I F C R W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A0AUR5 446 50092 P22 R P S G G G V P A S L F R R W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VWN5 560 61736 R110 L L W G D N V R E D V F K R W
Honey Bee Apis mellifera XP_396280 433 49407 I22 E G G P C A V I A P V Q A F I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001197555 419 47074 D22 S S V V N P V D E V R A M T W
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001145800 620 67621 A24 S L Q G S P P A Q P E P K R S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 87 N.A. 95.7 95 N.A. 88.1 86.9 N.A. 73.9 N.A. 38 35.9 N.A. 43.6
Protein Similarity: 100 100 N.A. 90 N.A. 97.7 97.9 N.A. 93.5 93 N.A. 86.7 N.A. 53.3 56.6 N.A. 63.1
P-Site Identity: 100 100 N.A. 6.6 N.A. 100 100 N.A. 46.6 60 N.A. 33.3 N.A. 20 0 N.A. 6.6
P-Site Similarity: 100 100 N.A. 13.3 N.A. 100 100 N.A. 53.3 66.6 N.A. 53.3 N.A. 40 13.3 N.A. 26.6
Percent
Protein Identity: N.A. 24.8 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 38.8 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 20 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 0 17 17 0 0 9 9 0 0 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 9 0 50 0 0 % C
% Asp: 0 0 0 0 9 0 0 9 42 9 0 0 0 0 0 % D
% Glu: 9 0 0 0 0 9 0 0 17 0 9 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 59 0 9 0 % F
% Gly: 0 9 17 34 9 59 0 0 9 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 9 % H
% Ile: 0 0 0 0 0 0 0 9 0 0 50 0 0 0 9 % I
% Lys: 9 34 0 0 0 0 0 0 0 0 0 0 25 0 0 % K
% Leu: 9 17 0 0 9 0 42 0 0 0 9 9 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 9 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 9 0 17 42 17 17 9 0 17 0 17 0 9 0 % P
% Gln: 0 9 9 0 0 0 0 0 9 0 0 9 0 0 0 % Q
% Arg: 9 0 0 0 9 0 0 17 9 0 9 0 9 67 0 % R
% Ser: 17 9 50 42 9 0 0 42 0 17 0 0 0 0 9 % S
% Thr: 42 9 0 0 0 0 0 0 0 42 0 0 0 9 9 % T
% Val: 0 9 9 9 0 0 34 0 0 9 17 0 0 9 0 % V
% Trp: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 67 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _