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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM188A
All Species:
37.58
Human Site:
Y399
Identified Species:
75.15
UniProt:
Q9H8M7
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H8M7
NP_079224.1
445
49725
Y399
N
Y
N
E
K
V
M
Y
V
E
G
T
A
V
V
Chimpanzee
Pan troglodytes
XP_001149628
445
49688
Y399
N
Y
N
E
K
V
M
Y
V
E
G
T
A
V
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544246
480
53561
Y434
N
Y
N
E
K
V
M
Y
V
E
G
T
A
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CV28
444
49594
Y398
N
Y
N
E
K
V
M
Y
V
E
G
T
A
V
V
Rat
Rattus norvegicus
NP_001099592
444
49484
Y398
N
Y
N
E
K
V
M
Y
V
E
G
T
A
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508622
447
50159
Y401
N
Y
N
E
K
V
M
Y
V
E
G
T
A
V
V
Chicken
Gallus gallus
XP_418629
445
50220
Y399
N
Y
N
E
K
V
M
Y
V
E
G
T
A
V
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A0AUR5
446
50092
Y400
N
H
N
E
K
V
S
Y
V
E
G
T
A
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VWN5
560
61736
Y515
N
E
N
N
K
V
R
Y
Y
C
G
T
A
I
L
Honey Bee
Apis mellifera
XP_396280
433
49407
Y388
N
P
E
N
K
V
I
Y
H
K
G
Q
A
V
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001197555
419
47074
F373
N
P
N
S
K
V
M
F
L
K
G
R
G
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001145800
620
67621
A538
V
P
N
G
N
A
S
A
G
G
S
C
P
I
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
87
N.A.
95.7
95
N.A.
88.1
86.9
N.A.
73.9
N.A.
38
35.9
N.A.
43.6
Protein Similarity:
100
100
N.A.
90
N.A.
97.7
97.9
N.A.
93.5
93
N.A.
86.7
N.A.
53.3
56.6
N.A.
63.1
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
N.A.
80
N.A.
53.3
46.6
N.A.
40
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
N.A.
66.6
66.6
N.A.
60
Percent
Protein Identity:
N.A.
24.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
38.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
9
0
0
0
0
84
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
9
67
0
0
0
0
0
67
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
9
9
92
0
9
0
0
% G
% His:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
0
0
0
17
0
% I
% Lys:
0
0
0
0
92
0
0
0
0
17
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
17
% L
% Met:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% M
% Asn:
92
0
92
17
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
25
0
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% Q
% Arg:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% R
% Ser:
0
0
0
9
0
0
17
0
0
0
9
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
75
0
0
0
% T
% Val:
9
0
0
0
0
92
0
0
67
0
0
0
0
67
67
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
59
0
0
0
0
0
84
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _