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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF395
All Species:
30
Human Site:
Y490
Identified Species:
60
UniProt:
Q9H8N7
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H8N7
NP_061130.1
513
54939
Y490
A
K
K
C
R
K
V
Y
G
I
E
H
R
D
Q
Chimpanzee
Pan troglodytes
XP_001166029
515
55077
Y492
A
K
K
C
R
K
V
Y
G
I
E
H
R
D
Q
Rhesus Macaque
Macaca mulatta
XP_001110395
512
55306
Y489
A
K
K
C
R
K
V
Y
G
I
E
H
R
D
Q
Dog
Lupus familis
XP_543220
500
54116
Y477
A
K
K
C
R
K
V
Y
G
I
E
H
R
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERQ3
566
61132
Y543
G
K
K
C
R
K
V
Y
G
M
E
N
R
D
M
Rat
Rattus norvegicus
NP_001100741
508
54911
Y485
A
K
K
C
R
K
V
Y
G
I
E
H
R
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505447
420
45522
D403
V
Y
G
T
D
N
R
D
L
W
C
T
A
C
R
Chicken
Gallus gallus
XP_420024
463
50241
D446
V
Y
G
I
E
H
R
D
Q
W
C
T
A
C
R
Frog
Xenopus laevis
Q6DFC8
498
54299
E478
C
R
K
V
Y
G
I
E
H
R
D
Q
W
C
T
Zebra Danio
Brachydanio rerio
Q1LY51
489
53922
Y466
G
K
K
C
R
K
V
Y
G
M
E
N
R
D
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120785
577
63164
Y554
T
K
K
C
R
K
V
Y
G
M
E
H
R
D
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782967
518
56769
Q498
H
I
E
Q
G
P
S
Q
V
S
T
S
Q
L
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96
86.3
N.A.
35.3
81.8
N.A.
34.5
60.6
62.5
35.6
N.A.
N.A.
22.5
N.A.
25.6
Protein Similarity:
100
99.4
97.2
89.4
N.A.
48
85.1
N.A.
45.4
66.8
72.9
49.9
N.A.
N.A.
34.3
N.A.
42.4
P-Site Identity:
100
100
100
100
N.A.
73.3
100
N.A.
0
0
6.6
73.3
N.A.
N.A.
80
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
100
N.A.
6.6
6.6
26.6
86.6
N.A.
N.A.
86.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% A
% Cys:
9
0
0
67
0
0
0
0
0
0
17
0
0
25
9
% C
% Asp:
0
0
0
0
9
0
0
17
0
0
9
0
0
67
0
% D
% Glu:
0
0
9
0
9
0
0
9
0
0
67
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
17
0
9
9
0
0
67
0
0
0
0
0
0
% G
% His:
9
0
0
0
0
9
0
0
9
0
0
50
0
0
0
% H
% Ile:
0
9
0
9
0
0
9
0
0
42
0
0
0
0
0
% I
% Lys:
0
67
75
0
0
67
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
17
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
0
17
0
0
0
% N
% Pro:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
9
9
0
0
9
9
0
42
% Q
% Arg:
0
9
0
0
67
0
17
0
0
9
0
0
67
0
17
% R
% Ser:
0
0
0
0
0
0
9
0
0
9
0
9
0
0
0
% S
% Thr:
9
0
0
9
0
0
0
0
0
0
9
17
0
0
9
% T
% Val:
17
0
0
9
0
0
67
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
17
0
0
9
0
0
% W
% Tyr:
0
17
0
0
9
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _