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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRD5A3
All Species:
15.15
Human Site:
S295
Identified Species:
27.78
UniProt:
Q9H8P0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H8P0
NP_078868.1
318
36521
S295
Q
A
L
S
A
F
L
S
H
Q
F
Y
K
S
K
Chimpanzee
Pan troglodytes
XP_001138166
318
36448
S295
Q
A
L
S
A
F
L
S
H
Q
F
Y
K
S
K
Rhesus Macaque
Macaca mulatta
XP_001088853
318
36454
S295
Q
A
L
S
A
F
L
S
H
Q
F
Y
K
S
K
Dog
Lupus familis
XP_539274
318
36661
S295
Q
A
L
C
A
L
L
S
H
K
F
Y
K
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUP4
330
37947
N307
Q
A
L
S
A
F
F
N
H
K
F
Y
R
S
T
Rat
Rattus norvegicus
P31214
254
28753
L236
F
Y
H
H
R
F
Y
L
K
M
F
K
D
Y
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420703
310
35604
C287
Q
T
L
A
A
V
L
C
H
E
F
Y
Q
E
K
Frog
Xenopus laevis
Q8AVI9
319
36573
C296
Q
A
L
A
A
V
L
C
H
E
F
Y
H
E
K
Zebra Danio
Brachydanio rerio
NP_001038404
309
35690
C286
Q
A
L
A
A
Q
L
C
H
E
Y
Y
R
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201930
186
21599
Q168
V
K
V
H
R
W
Y
Q
G
K
F
E
D
Y
P
Poplar Tree
Populus trichocarpa
XP_002313005
339
38859
T316
L
V
F
A
A
A
E
T
H
R
W
Y
L
Q
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38944
262
30616
A244
A
S
H
K
W
Y
I
A
K
F
K
E
E
Y
P
Baker's Yeast
Sacchar. cerevisiae
P40526
253
30287
R235
L
E
T
K
N
Y
Y
R
H
K
F
K
D
N
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.4
90.5
N.A.
78.1
27.3
N.A.
N.A.
54
51.4
42.7
N.A.
N.A.
N.A.
N.A.
28.3
Protein Similarity:
100
99.6
99
93.7
N.A.
83.6
38.6
N.A.
N.A.
66
66.1
59.4
N.A.
N.A.
N.A.
N.A.
40.2
P-Site Identity:
100
100
100
73.3
N.A.
66.6
13.3
N.A.
N.A.
53.3
60
60
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
86.6
13.3
N.A.
N.A.
73.3
73.3
86.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
33.6
N.A.
N.A.
25.1
24.5
N.A.
Protein Similarity:
51.6
N.A.
N.A.
40.8
42.7
N.A.
P-Site Identity:
26.6
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
54
0
31
70
8
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
24
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
24
0
0
% D
% Glu:
0
8
0
0
0
0
8
0
0
24
0
16
8
16
0
% E
% Phe:
8
0
8
0
0
39
8
0
0
8
77
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
16
16
0
0
0
0
77
0
0
0
8
0
8
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
16
0
0
0
0
16
31
8
16
31
0
54
% K
% Leu:
16
0
62
0
0
8
54
8
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
0
0
0
8
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
24
% P
% Gln:
62
0
0
0
0
8
0
8
0
24
0
0
8
8
0
% Q
% Arg:
0
0
0
0
16
0
0
8
0
8
0
0
16
0
0
% R
% Ser:
0
8
0
31
0
0
0
31
0
0
0
0
0
47
0
% S
% Thr:
0
8
8
0
0
0
0
8
0
0
0
0
0
0
8
% T
% Val:
8
8
8
0
0
16
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
8
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
8
0
0
0
16
24
0
0
0
8
70
0
24
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _