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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRD5A3 All Species: 16.36
Human Site: T55 Identified Species: 30
UniProt: Q9H8P0 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H8P0 NP_078868.1 318 36521 T55 D L I R Y G K T K C G E P S R
Chimpanzee Pan troglodytes XP_001138166 318 36448 T55 D L I R Y G K T K C G E P S R
Rhesus Macaque Macaca mulatta XP_001088853 318 36454 T55 D L I R Y G K T K C G E P P R
Dog Lupus familis XP_539274 318 36661 T55 D L I R Y G K T K R E G P S R
Cat Felis silvestris
Mouse Mus musculus Q9WUP4 330 37947 T55 D L L R Y G K T K Q S G S R R
Rat Rattus norvegicus P31214 254 28753 L27 M G T L I L C L G K P A S Y G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420703 310 35604 K49 Q D L I R Y G K T K R G G Q Q
Frog Xenopus laevis Q8AVI9 319 36573 K56 Q D L I R Y G K T K S G L R R
Zebra Danio Brachydanio rerio NP_001038404 309 35690 K48 Q D F I R Y G K T K E N I K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001201930 186 21599
Poplar Tree Populus trichocarpa XP_002313005 339 38859 H52 K I M Q S S S H R K F T V P Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38944 262 30616 Y35 L K F L Q A P Y G K H N R T G
Baker's Yeast Sacchar. cerevisiae P40526 253 30287 S26 S F F V G I C S L F I A K S C
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.4 90.5 N.A. 78.1 27.3 N.A. N.A. 54 51.4 42.7 N.A. N.A. N.A. N.A. 28.3
Protein Similarity: 100 99.6 99 93.7 N.A. 83.6 38.6 N.A. N.A. 66 66.1 59.4 N.A. N.A. N.A. N.A. 40.2
P-Site Identity: 100 100 93.3 80 N.A. 60 0 N.A. N.A. 0 6.6 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 93.3 80 N.A. 66.6 0 N.A. N.A. 13.3 13.3 6.6 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: 33.6 N.A. N.A. 25.1 24.5 N.A.
Protein Similarity: 51.6 N.A. N.A. 40.8 42.7 N.A.
P-Site Identity: 0 N.A. N.A. 0 6.6 N.A.
P-Site Similarity: 33.3 N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 0 0 0 16 0 0 0 % A
% Cys: 0 0 0 0 0 0 16 0 0 24 0 0 0 0 8 % C
% Asp: 39 24 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 16 24 0 0 0 % E
% Phe: 0 8 24 0 0 0 0 0 0 8 8 0 0 0 0 % F
% Gly: 0 8 0 0 8 39 24 0 16 0 24 31 8 0 16 % G
% His: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % H
% Ile: 0 8 31 24 8 8 0 0 0 0 8 0 8 0 0 % I
% Lys: 8 8 0 0 0 0 39 24 39 47 0 0 8 8 0 % K
% Leu: 8 39 24 16 0 8 0 8 8 0 0 0 8 0 0 % L
% Met: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % N
% Pro: 0 0 0 0 0 0 8 0 0 0 8 0 31 16 0 % P
% Gln: 24 0 0 8 8 0 0 0 0 8 0 0 0 8 16 % Q
% Arg: 0 0 0 39 24 0 0 0 8 8 8 0 8 16 54 % R
% Ser: 8 0 0 0 8 8 8 8 0 0 16 0 16 31 0 % S
% Thr: 0 0 8 0 0 0 0 39 24 0 0 8 0 8 0 % T
% Val: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 39 24 0 8 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _