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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRD5A3
All Species:
19.09
Human Site:
Y189
Identified Species:
35
UniProt:
Q9H8P0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H8P0
NP_078868.1
318
36521
Y189
P
M
D
G
R
N
A
Y
I
T
G
K
N
L
L
Chimpanzee
Pan troglodytes
XP_001138166
318
36448
Y189
P
M
D
G
R
N
A
Y
I
T
G
K
N
L
L
Rhesus Macaque
Macaca mulatta
XP_001088853
318
36454
Y189
P
M
D
G
R
N
A
Y
V
T
G
K
N
V
L
Dog
Lupus familis
XP_539274
318
36661
Y189
P
M
D
G
R
N
V
Y
V
I
G
K
N
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUP4
330
37947
Y201
P
M
D
D
K
N
V
Y
V
L
G
K
N
L
L
Rat
Rattus norvegicus
P31214
254
28753
I154
S
F
G
V
F
L
F
I
L
G
M
G
I
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420703
310
35604
K185
P
T
N
V
R
N
G
K
G
L
S
V
H
I
F
Frog
Xenopus laevis
Q8AVI9
319
36573
V191
P
L
D
R
R
T
A
V
S
L
D
D
L
L
M
Zebra Danio
Brachydanio rerio
NP_001038404
309
35690
S183
D
S
L
P
Q
S
E
S
V
S
F
F
N
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201930
186
21599
W86
L
M
F
V
W
A
S
W
H
H
H
I
A
H
V
Poplar Tree
Populus trichocarpa
XP_002313005
339
38859
G191
A
P
E
V
L
K
F
G
I
N
E
V
S
E
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38944
262
30616
T162
I
G
M
V
V
F
I
T
G
M
Y
I
N
I
T
Baker's Yeast
Sacchar. cerevisiae
P40526
253
30287
M153
S
I
P
N
T
L
N
M
N
A
F
I
I
F
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.4
90.5
N.A.
78.1
27.3
N.A.
N.A.
54
51.4
42.7
N.A.
N.A.
N.A.
N.A.
28.3
Protein Similarity:
100
99.6
99
93.7
N.A.
83.6
38.6
N.A.
N.A.
66
66.1
59.4
N.A.
N.A.
N.A.
N.A.
40.2
P-Site Identity:
100
100
86.6
80
N.A.
66.6
0
N.A.
N.A.
20
33.3
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
80
13.3
N.A.
N.A.
40
46.6
40
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
33.6
N.A.
N.A.
25.1
24.5
N.A.
Protein Similarity:
51.6
N.A.
N.A.
40.8
42.7
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
20
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
31
0
0
8
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
0
47
8
0
0
0
0
0
0
8
8
0
0
0
% D
% Glu:
0
0
8
0
0
0
8
0
0
0
8
0
0
8
0
% E
% Phe:
0
8
8
0
8
8
16
0
0
0
16
8
0
8
16
% F
% Gly:
0
8
8
31
0
0
8
8
16
8
39
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
8
8
0
8
8
0
% H
% Ile:
8
8
0
0
0
0
8
8
24
8
0
24
16
16
8
% I
% Lys:
0
0
0
0
8
8
0
8
0
0
0
39
0
0
0
% K
% Leu:
8
8
8
0
8
16
0
0
8
24
0
0
8
39
47
% L
% Met:
0
47
8
0
0
0
0
8
0
8
8
0
0
0
8
% M
% Asn:
0
0
8
8
0
47
8
0
8
8
0
0
54
8
0
% N
% Pro:
54
8
8
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
8
47
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
16
8
0
0
0
8
8
8
8
8
8
0
8
0
0
% S
% Thr:
0
8
0
0
8
8
0
8
0
24
0
0
0
0
8
% T
% Val:
0
0
0
39
8
0
16
8
31
0
0
16
0
8
8
% V
% Trp:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
39
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _