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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRD5A3
All Species:
17.88
Human Site:
Y250
Identified Species:
32.78
UniProt:
Q9H8P0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H8P0
NP_078868.1
318
36521
Y250
P
F
G
D
W
F
E
Y
V
S
S
P
N
Y
L
Chimpanzee
Pan troglodytes
XP_001138166
318
36448
Y250
P
F
G
D
W
F
E
Y
V
S
S
P
N
Y
L
Rhesus Macaque
Macaca mulatta
XP_001088853
318
36454
Y250
P
F
G
D
W
F
E
Y
V
S
S
P
N
Y
L
Dog
Lupus familis
XP_539274
318
36661
Y250
P
F
G
D
W
F
E
Y
V
S
S
P
N
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUP4
330
37947
Y262
P
F
G
D
W
F
E
Y
V
S
S
A
N
Y
L
Rat
Rattus norvegicus
P31214
254
28753
G191
G
L
F
T
Y
V
S
G
A
N
F
L
G
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420703
310
35604
R242
P
F
G
D
W
F
E
R
V
S
C
P
H
Y
F
Frog
Xenopus laevis
Q8AVI9
319
36573
K251
P
T
G
D
W
F
E
K
V
S
C
P
H
Y
F
Zebra Danio
Brachydanio rerio
NP_001038404
309
35690
L241
P
C
G
G
W
F
E
L
V
S
C
P
H
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201930
186
21599
H123
F
D
Y
V
S
C
P
H
Y
L
A
E
T
L
I
Poplar Tree
Populus trichocarpa
XP_002313005
339
38859
I271
P
R
G
D
W
F
E
I
V
S
S
P
H
Y
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38944
262
30616
P199
W
F
E
L
V
S
C
P
N
Y
F
G
E
A
I
Baker's Yeast
Sacchar. cerevisiae
P40526
253
30287
V190
T
G
R
L
F
R
L
V
C
C
P
H
Y
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.4
90.5
N.A.
78.1
27.3
N.A.
N.A.
54
51.4
42.7
N.A.
N.A.
N.A.
N.A.
28.3
Protein Similarity:
100
99.6
99
93.7
N.A.
83.6
38.6
N.A.
N.A.
66
66.1
59.4
N.A.
N.A.
N.A.
N.A.
40.2
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
N.A.
73.3
66.6
66.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
20
N.A.
N.A.
80
73.3
73.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
33.6
N.A.
N.A.
25.1
24.5
N.A.
Protein Similarity:
51.6
N.A.
N.A.
40.8
42.7
N.A.
P-Site Identity:
80
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
86.6
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
8
8
0
8
0
% A
% Cys:
0
8
0
0
0
8
8
0
8
8
24
0
0
0
0
% C
% Asp:
0
8
0
62
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
8
0
0
0
70
0
0
0
0
8
8
8
0
% E
% Phe:
8
54
8
0
8
70
0
0
0
0
16
0
0
0
16
% F
% Gly:
8
8
70
8
0
0
0
8
0
0
0
8
8
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
8
31
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
24
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
16
0
0
8
8
0
8
0
8
0
16
54
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
8
0
0
39
0
0
% N
% Pro:
70
0
0
0
0
0
8
8
0
0
8
62
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
8
0
0
8
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
8
8
0
0
70
47
0
0
0
0
% S
% Thr:
8
8
0
8
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
0
0
8
8
8
0
8
70
0
0
0
0
0
0
% V
% Trp:
8
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
0
39
8
8
0
0
8
70
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _