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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AKTIP All Species: 41.21
Human Site: Y234 Identified Species: 69.74
UniProt: Q9H8T0 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H8T0 NP_001012398.1 292 33128 Y234 Q P K I E D P Y A I S F S P W
Chimpanzee Pan troglodytes XP_001166382 293 33238 Y234 Q P K I E D P Y A I S F S P W
Rhesus Macaque Macaca mulatta XP_001085712 292 33132 Y234 Q P K I E D P Y A I S F S P W
Dog Lupus familis XP_863328 286 32246 Y228 Q P K I E D P Y A I S F S P W
Cat Felis silvestris
Mouse Mus musculus Q64362 292 32923 Y234 Q P K I E D P Y A I S F S P W
Rat Rattus norvegicus Q5FVH4 292 32973 Y234 Q P K I E D P Y A I S F S P W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520209 412 45602 Y351 Q P K I E D P Y A I R R V A S
Chicken Gallus gallus Q5ZJJ5 293 33286 Y234 Q P K I E D P Y A I V F S P W
Frog Xenopus laevis Q498F8 293 33438 Y235 Q P K I E D P Y A I I F S P W
Zebra Danio Brachydanio rerio Q7ZYX1 293 33182 Y235 Q P K I D D P Y A I S F S P W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K4V4 244 28114 P187 D T P P T E D P H Y I V F E K
Honey Bee Apis mellifera XP_625209 266 31023 S209 S L N K V Y N S S T V D D P H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784185 277 31591 Y219 L K R Y D P P Y S D D P H A I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P52490 153 17450 S96 D V L K T N W S P A L Q I R T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.6 95.2 N.A. 96.2 95.8 N.A. 59.9 87.3 82.9 78.1 N.A. 32.8 35.6 N.A. 53.4
Protein Similarity: 100 99.6 99.6 95.8 N.A. 97.9 98.6 N.A. 63.8 94.8 91.1 88 N.A. 46.9 59.2 N.A. 68.4
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 66.6 93.3 93.3 93.3 N.A. 0 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 66.6 93.3 93.3 100 N.A. 6.6 13.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 34.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 72 8 0 0 0 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 0 0 0 15 72 8 0 0 8 8 8 8 0 0 % D
% Glu: 0 0 0 0 65 8 0 0 0 0 0 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 65 8 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 8 % H
% Ile: 0 0 0 72 0 0 0 0 0 72 15 0 8 0 8 % I
% Lys: 0 8 72 15 0 0 0 0 0 0 0 0 0 0 8 % K
% Leu: 8 8 8 0 0 0 0 0 0 0 8 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 8 8 0 0 0 0 0 0 0 0 % N
% Pro: 0 72 8 8 0 8 79 8 8 0 0 8 0 72 0 % P
% Gln: 72 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 8 8 0 8 0 % R
% Ser: 8 0 0 0 0 0 0 15 15 0 50 0 65 0 8 % S
% Thr: 0 8 0 0 15 0 0 0 0 8 0 0 0 0 8 % T
% Val: 0 8 0 0 8 0 0 0 0 0 15 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 65 % W
% Tyr: 0 0 0 8 0 8 0 79 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _