KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHF2
All Species:
18.18
Human Site:
S195
Identified Species:
36.36
UniProt:
Q9H8W4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H8W4
NP_078889.1
249
27798
S195
E
K
R
F
L
L
P
S
Q
S
S
K
P
V
R
Chimpanzee
Pan troglodytes
XP_512558
279
31146
R195
R
Q
R
F
L
L
P
R
L
S
P
K
P
V
R
Rhesus Macaque
Macaca mulatta
XP_001084522
279
31261
R195
R
Q
R
F
L
L
P
R
L
S
P
K
P
V
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q91WB4
249
27736
S195
E
K
R
F
L
L
P
S
Q
S
S
K
P
V
R
Rat
Rattus norvegicus
Q68FU1
279
31422
R195
R
E
R
F
L
L
P
R
L
S
P
K
P
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510746
249
27749
S195
E
K
R
F
L
L
P
S
Q
S
S
K
P
V
R
Chicken
Gallus gallus
Q5ZLY5
249
27697
S195
E
K
R
F
L
L
P
S
Q
S
S
K
P
V
R
Frog
Xenopus laevis
NP_001091185
248
27817
S195
E
K
K
Y
L
L
P
S
Q
S
S
K
P
V
R
Zebra Danio
Brachydanio rerio
Q7ZUV1
247
27424
L192
P
C
S
E
K
K
F
L
L
P
S
Q
S
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624027
268
29804
G195
N
K
K
L
L
L
P
G
Q
G
N
G
K
A
V
Nematode Worm
Caenorhab. elegans
P34657
266
30169
N195
S
R
T
F
R
I
D
N
V
H
K
K
P
V
R
Sea Urchin
Strong. purpuratus
XP_783303
377
42354
L305
A
K
K
F
L
L
P
L
Q
S
E
A
P
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.5
50.5
N.A.
N.A.
97.5
48
N.A.
93.1
94.7
85.1
84.3
N.A.
N.A.
61.5
54.1
41.1
Protein Similarity:
100
65.2
65.2
N.A.
N.A.
98.3
63
N.A.
97.1
96.3
95.1
91.5
N.A.
N.A.
72.3
66.1
50.1
P-Site Identity:
100
66.6
66.6
N.A.
N.A.
100
60
N.A.
100
100
86.6
6.6
N.A.
N.A.
33.3
33.3
66.6
P-Site Similarity:
100
73.3
73.3
N.A.
N.A.
100
73.3
N.A.
100
100
100
20
N.A.
N.A.
46.6
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% D
% Glu:
42
9
0
9
0
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
75
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
9
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
59
25
0
9
9
0
0
0
0
9
75
9
0
9
% K
% Leu:
0
0
0
9
84
84
0
17
34
0
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
84
0
0
9
25
0
84
0
0
% P
% Gln:
0
17
0
0
0
0
0
0
59
0
0
9
0
0
0
% Q
% Arg:
25
9
59
0
9
0
0
25
0
0
0
0
0
0
84
% R
% Ser:
9
0
9
0
0
0
0
42
0
75
50
0
9
9
0
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
0
0
0
0
75
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _