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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHF2
All Species:
44.55
Human Site:
T104
Identified Species:
89.09
UniProt:
Q9H8W4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H8W4
NP_078889.1
249
27798
T104
R
N
G
W
L
I
K
T
P
T
K
S
F
A
V
Chimpanzee
Pan troglodytes
XP_512558
279
31146
T104
K
N
R
W
M
I
K
T
A
K
K
S
F
V
V
Rhesus Macaque
Macaca mulatta
XP_001084522
279
31261
T104
K
N
R
W
M
I
K
T
A
K
K
S
F
V
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q91WB4
249
27736
T104
R
N
G
W
L
I
K
T
P
T
K
S
F
A
V
Rat
Rattus norvegicus
Q68FU1
279
31422
T104
K
N
R
W
M
I
K
T
A
K
K
S
F
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510746
249
27749
T104
R
N
G
W
L
I
K
T
P
T
K
S
F
A
V
Chicken
Gallus gallus
Q5ZLY5
249
27697
T104
R
N
G
W
L
I
K
T
P
T
K
S
F
A
V
Frog
Xenopus laevis
NP_001091185
248
27817
T104
R
N
G
W
L
I
K
T
P
T
K
S
F
A
V
Zebra Danio
Brachydanio rerio
Q7ZUV1
247
27424
T104
R
N
G
W
L
I
K
T
P
T
K
S
F
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624027
268
29804
T104
R
N
G
W
L
I
K
T
V
T
K
S
F
A
V
Nematode Worm
Caenorhab. elegans
P34657
266
30169
T104
K
H
G
W
I
I
K
T
P
A
K
S
F
A
V
Sea Urchin
Strong. purpuratus
XP_783303
377
42354
S215
K
N
G
W
Q
I
I
S
A
T
K
S
F
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.5
50.5
N.A.
N.A.
97.5
48
N.A.
93.1
94.7
85.1
84.3
N.A.
N.A.
61.5
54.1
41.1
Protein Similarity:
100
65.2
65.2
N.A.
N.A.
98.3
63
N.A.
97.1
96.3
95.1
91.5
N.A.
N.A.
72.3
66.1
50.1
P-Site Identity:
100
60
60
N.A.
N.A.
100
60
N.A.
100
100
100
100
N.A.
N.A.
93.3
73.3
60
P-Site Similarity:
100
73.3
73.3
N.A.
N.A.
100
73.3
N.A.
100
100
100
100
N.A.
N.A.
93.3
93.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
34
9
0
0
0
67
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% F
% Gly:
0
0
75
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
100
9
0
0
0
0
0
0
0
0
% I
% Lys:
42
0
0
0
0
0
92
0
0
25
100
0
0
0
0
% K
% Leu:
0
0
0
0
59
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
25
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
92
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
59
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
59
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
9
0
0
0
100
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
92
0
67
0
0
0
9
0
% T
% Val:
0
0
0
0
0
0
0
0
9
0
0
0
0
25
100
% V
% Trp:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _