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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIM45
All Species:
17.88
Human Site:
S451
Identified Species:
65.56
UniProt:
Q9H8W5
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H8W5
NP_079464.2
580
64359
S451
V
P
K
D
K
K
D
S
P
V
R
T
M
V
Q
Chimpanzee
Pan troglodytes
XP_001145514
580
64336
S451
V
P
K
D
K
K
D
S
P
V
R
T
M
V
Q
Rhesus Macaque
Macaca mulatta
XP_001113153
580
64211
S451
L
P
K
D
K
K
D
S
P
V
R
P
M
V
Q
Dog
Lupus familis
XP_533020
580
63668
S451
V
P
K
D
K
K
D
S
P
V
R
T
L
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6PFY8
580
64167
S451
V
P
K
D
K
K
D
S
P
I
R
T
V
V
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609193
921
101527
N792
C
H
G
G
L
E
I
N
C
M
L
K
Y
K
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796095
618
67889
R444
L
A
I
E
G
R
T
R
A
Y
P
C
K
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
96.5
91.3
N.A.
85.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
22.9
N.A.
N.A.
33.8
Protein Similarity:
100
98.9
98
94.6
N.A.
92.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
54.2
P-Site Identity:
100
100
86.6
93.3
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
0
0
0
15
0
0
0
0
0
15
% A
% Cys:
15
0
0
0
0
0
0
0
15
0
0
15
0
0
0
% C
% Asp:
0
0
0
72
0
0
72
0
0
0
0
0
0
0
15
% D
% Glu:
0
0
0
15
0
15
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
15
15
15
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
15
0
0
0
15
0
0
15
0
0
0
0
0
% I
% Lys:
0
0
72
0
72
72
0
0
0
0
0
15
15
15
0
% K
% Leu:
29
0
0
0
15
0
0
0
0
0
15
0
15
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
15
0
0
43
0
0
% M
% Asn:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% N
% Pro:
0
72
0
0
0
0
0
0
72
0
15
15
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
72
% Q
% Arg:
0
0
0
0
0
15
0
15
0
0
72
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
72
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
15
0
0
0
0
58
0
0
0
% T
% Val:
58
0
0
0
0
0
0
0
0
58
0
0
15
86
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
15
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _