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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIM45
All Species:
20.91
Human Site:
S491
Identified Species:
76.67
UniProt:
Q9H8W5
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H8W5
NP_079464.2
580
64359
S491
K
E
Q
H
V
Q
G
S
P
F
T
V
M
V
R
Chimpanzee
Pan troglodytes
XP_001145514
580
64336
S491
K
E
Q
H
V
Q
G
S
P
F
T
V
T
V
R
Rhesus Macaque
Macaca mulatta
XP_001113153
580
64211
S491
K
E
Q
H
V
Q
G
S
P
F
T
V
T
V
R
Dog
Lupus familis
XP_533020
580
63668
S491
K
E
Q
H
V
Q
G
S
P
F
T
V
T
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6PFY8
580
64167
S491
R
E
Q
H
V
Q
G
S
P
F
N
V
T
V
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609193
921
101527
T832
A
Q
G
T
L
I
L
T
I
T
I
N
D
R
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796095
618
67889
S484
N
G
H
H
I
R
G
S
P
F
S
V
S
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
96.5
91.3
N.A.
85.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
22.9
N.A.
N.A.
33.8
Protein Similarity:
100
98.9
98
94.6
N.A.
92.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
54.2
P-Site Identity:
100
93.3
93.3
93.3
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
46.6
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% D
% Glu:
0
72
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
86
0
0
0
0
0
% F
% Gly:
0
15
15
0
0
0
86
0
0
0
0
0
0
0
0
% G
% His:
0
0
15
86
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
15
15
0
0
15
0
15
0
0
0
0
% I
% Lys:
58
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% K
% Leu:
0
0
0
0
15
0
15
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% M
% Asn:
15
0
0
0
0
0
0
0
0
0
15
15
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
86
0
0
0
0
0
15
% P
% Gln:
0
15
72
0
0
72
0
0
0
0
0
0
0
0
0
% Q
% Arg:
15
0
0
0
0
15
0
0
0
0
0
0
0
15
72
% R
% Ser:
0
0
0
0
0
0
0
86
0
0
15
0
15
0
0
% S
% Thr:
0
0
0
15
0
0
0
15
0
15
58
0
58
0
0
% T
% Val:
0
0
0
0
72
0
0
0
0
0
0
86
0
86
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _