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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IPPK
All Species:
23.33
Human Site:
Y186
Identified Species:
57.04
UniProt:
Q9H8X2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H8X2
NP_073592.1
491
56017
Y186
K
Y
C
P
L
D
L
Y
S
G
N
K
Q
R
M
Chimpanzee
Pan troglodytes
XP_001146820
491
55938
Y186
K
Y
C
P
L
D
L
Y
S
G
N
K
Q
R
M
Rhesus Macaque
Macaca mulatta
XP_001103030
491
56026
Y186
R
Y
C
P
L
D
L
Y
S
G
N
K
Q
R
M
Dog
Lupus familis
XP_541331
692
76945
Y389
K
Y
C
P
L
D
L
Y
S
G
N
K
Q
R
M
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1C1
489
55909
Y186
K
Y
C
P
L
D
L
Y
S
G
N
K
Q
R
M
Rat
Rattus norvegicus
Q5PXE9
489
55616
Y186
K
Y
C
P
L
D
L
Y
S
G
N
K
Q
R
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519606
207
23636
Chicken
Gallus gallus
XP_414295
491
56589
F186
K
Y
C
P
V
D
L
F
S
G
N
K
Q
R
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q4JL91
483
56009
S182
N
G
K
W
K
R
L
S
R
Y
C
P
L
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001106063
440
48948
D140
S
S
I
D
N
T
A
D
A
A
L
L
I
A
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.7
65
N.A.
91
91.8
N.A.
35.8
79.8
N.A.
55.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99.1
67.3
N.A.
93.4
93.8
N.A.
39.9
88.5
N.A.
71.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
0
86.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
100
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
20.1
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
37.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
10
10
0
0
0
10
0
% A
% Cys:
0
0
70
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
10
0
70
0
10
0
0
0
0
0
10
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
70
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
60
0
10
0
10
0
0
0
0
0
0
70
0
0
0
% K
% Leu:
0
0
0
0
60
0
80
0
0
0
10
10
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% M
% Asn:
10
0
0
0
10
0
0
0
0
0
70
0
0
0
0
% N
% Pro:
0
0
0
70
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
70
0
0
% Q
% Arg:
10
0
0
0
0
10
0
0
10
0
0
0
0
70
0
% R
% Ser:
10
10
0
0
0
0
0
10
70
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
70
0
0
0
0
0
60
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _