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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IPPK
All Species:
29.09
Human Site:
Y445
Identified Species:
71.11
UniProt:
Q9H8X2
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H8X2
NP_073592.1
491
56017
Y445
L
D
L
D
L
K
P
Y
E
S
I
P
H
Q
Y
Chimpanzee
Pan troglodytes
XP_001146820
491
55938
Y445
L
D
L
D
L
K
P
Y
E
S
I
P
H
Q
Y
Rhesus Macaque
Macaca mulatta
XP_001103030
491
56026
Y445
L
D
L
D
L
K
P
Y
E
S
I
P
H
Q
Y
Dog
Lupus familis
XP_541331
692
76945
Y646
L
D
L
D
L
K
P
Y
E
S
I
P
H
Q
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1C1
489
55909
Y443
L
D
L
D
L
K
P
Y
E
S
I
P
H
Q
Y
Rat
Rattus norvegicus
Q5PXE9
489
55616
Y443
L
D
L
D
L
K
P
Y
E
S
I
P
H
Q
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519606
207
23636
K161
H
C
T
R
T
I
I
K
E
L
I
H
V
I
T
Chicken
Gallus gallus
XP_414295
491
56589
Y445
L
D
L
D
L
K
P
Y
E
S
I
P
H
Q
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q4JL91
483
56009
T437
V
S
I
L
D
L
D
T
K
P
Y
E
G
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001106063
440
48948
T395
F
L
E
S
V
K
R
T
Y
E
Y
K
A
Y
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.7
65
N.A.
91
91.8
N.A.
35.8
79.8
N.A.
55.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99.1
67.3
N.A.
93.4
93.8
N.A.
39.9
88.5
N.A.
71.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
20.1
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
37.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
70
0
70
10
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
80
10
0
10
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
10
70
0
0
% H
% Ile:
0
0
10
0
0
10
10
0
0
0
80
0
0
20
0
% I
% Lys:
0
0
0
0
0
80
0
10
10
0
0
10
0
0
0
% K
% Leu:
70
10
70
10
70
10
0
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
70
0
0
10
0
70
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
70
0
% Q
% Arg:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
10
0
0
0
0
0
70
0
0
0
0
0
% S
% Thr:
0
0
10
0
10
0
0
20
0
0
0
0
0
0
10
% T
% Val:
10
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
10
0
20
0
0
10
70
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _