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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZWILCH
All Species:
35.15
Human Site:
Y498
Identified Species:
85.93
UniProt:
Q9H900
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H900
NP_060445.3
591
67214
Y498
L
T
Q
I
C
I
K
Y
Y
K
Q
N
P
L
D
Chimpanzee
Pan troglodytes
XP_510495
591
67226
Y498
L
T
Q
I
C
I
K
Y
Y
K
Q
N
P
L
D
Rhesus Macaque
Macaca mulatta
XP_001110821
593
67261
Y500
L
T
Q
I
C
I
K
Y
Y
K
Q
N
P
L
D
Dog
Lupus familis
XP_535523
362
40706
Y273
A
S
L
N
H
L
E
Y
F
I
T
P
S
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8R060
589
66821
Y496
L
T
Q
S
C
I
K
Y
Y
K
Q
N
P
L
D
Rat
Rattus norvegicus
XP_002727092
549
62496
Y456
L
T
Q
S
C
I
K
Y
Y
K
Q
N
P
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511193
605
68061
Y500
L
T
Q
S
C
I
K
Y
Y
Q
Q
N
P
L
N
Chicken
Gallus gallus
XP_413922
596
67141
Y500
L
T
Q
T
C
L
K
Y
Y
K
E
N
P
L
N
Frog
Xenopus laevis
Q6IRM9
597
67361
Y501
L
T
Q
S
C
L
K
Y
Y
K
E
N
P
W
N
Zebra Danio
Brachydanio rerio
A5WWB6
583
66060
Y488
F
T
Q
S
C
L
Q
Y
Y
K
T
S
N
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
89.7
53.4
N.A.
80.7
76.9
N.A.
64.1
55.2
50.9
42.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
92.7
57.7
N.A.
88.8
83.7
N.A.
79
72.4
71.1
60.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
93.3
93.3
N.A.
80
73.3
66.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
46.6
N.A.
93.3
93.3
N.A.
93.3
93.3
86.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
90
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
20
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
30
0
60
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
80
0
0
80
0
0
0
0
0
% K
% Leu:
80
0
10
0
0
40
0
0
0
0
0
0
0
70
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
80
10
0
30
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
80
0
0
% P
% Gln:
0
0
90
0
0
0
10
0
0
10
60
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
50
0
0
0
0
0
0
0
10
10
0
0
% S
% Thr:
0
90
0
10
0
0
0
0
0
0
20
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
100
90
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _