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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REEP1
All Species:
6.36
Human Site:
S196
Identified Species:
14
UniProt:
Q9H902
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H902
NP_075063.1
201
22255
S196
R
S
A
S
E
S
A
S
S
S
G
T
A
_
_
Chimpanzee
Pan troglodytes
XP_001137837
205
22641
S200
R
S
A
S
E
S
A
S
S
S
G
T
A
_
_
Rhesus Macaque
Macaca mulatta
XP_001085977
188
20830
Dog
Lupus familis
XP_854822
301
33410
G296
R
S
A
S
E
S
A
G
S
S
G
T
A
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGH4
201
22266
G196
R
S
A
S
E
S
A
G
S
S
G
T
A
_
_
Rat
Rattus norvegicus
Q4QQW1
257
29642
T196
G
G
L
Q
D
S
D
T
E
D
E
C
W
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235011
287
32024
D218
S
E
G
T
G
S
S
D
V
N
D
K
Y
E
K
Frog
Xenopus laevis
NP_001083678
263
30121
D196
G
F
G
S
L
R
K
D
S
G
D
D
N
T
D
Zebra Danio
Brachydanio rerio
Q4KMI4
268
30092
A196
V
R
A
T
P
V
P
A
D
T
E
S
Q
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10010
229
26592
F213
D
S
G
A
D
S
E
F
T
T
A
A
T
I
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GXE9
258
29531
S238
I
P
D
T
I
P
G
S
P
L
T
D
A
R
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.6
86
65.7
N.A.
98
54.4
N.A.
N.A.
52.6
50.9
54.8
N.A.
N.A.
N.A.
41
N.A.
Protein Similarity:
100
94.1
89
65.7
N.A.
99
63.8
N.A.
N.A.
56.7
61.5
64.9
N.A.
N.A.
N.A.
58.5
N.A.
P-Site Identity:
100
100
0
92.3
N.A.
92.3
6.6
N.A.
N.A.
6.6
13.3
6.6
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
0
92.3
N.A.
92.3
20
N.A.
N.A.
26.6
13.3
33.3
N.A.
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
46
10
0
0
37
10
0
0
10
10
46
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
10
0
10
0
19
0
10
19
10
10
19
19
0
0
19
% D
% Glu:
0
10
0
0
37
0
10
0
10
0
19
0
0
10
0
% E
% Phe:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
19
10
28
0
10
0
10
19
0
10
37
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
10
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
10
% K
% Leu:
0
0
10
0
10
0
0
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% N
% Pro:
0
10
0
0
10
10
10
0
10
0
0
0
0
0
10
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
37
10
0
0
0
10
0
0
0
0
0
0
0
10
0
% R
% Ser:
10
46
0
46
0
64
10
28
46
37
0
10
0
10
10
% S
% Thr:
0
0
0
28
0
0
0
10
10
19
10
37
10
10
0
% T
% Val:
10
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
37
37
% _