KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTHFD2L
All Species:
38.79
Human Site:
T191
Identified Species:
77.58
UniProt:
Q9H903
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H903
NP_001138450.1
289
31285
T191
V
T
I
A
H
R
Y
T
P
K
E
Q
L
K
I
Chimpanzee
Pan troglodytes
XP_517226
379
40691
T281
V
T
I
A
H
R
Y
T
P
K
E
Q
L
K
I
Rhesus Macaque
Macaca mulatta
XP_001091218
502
54417
T404
V
T
I
A
H
R
Y
T
P
K
E
Q
L
K
I
Dog
Lupus familis
XP_539316
310
33584
T212
V
T
I
A
H
R
Y
T
P
K
E
Q
L
K
I
Cat
Felis silvestris
Mouse
Mus musculus
P18155
350
37844
T235
V
T
I
S
H
R
Y
T
P
K
E
Q
L
K
K
Rat
Rattus norvegicus
NP_001100681
338
36408
T240
V
T
I
A
H
R
H
T
P
R
E
Q
L
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511115
253
27145
H163
P
R
E
Q
L
R
M
H
C
Q
L
A
D
I
I
Chicken
Gallus gallus
Q5ZKA5
337
36393
T230
V
T
I
S
H
R
Y
T
P
K
E
Q
L
K
Q
Frog
Xenopus laevis
NP_001085223
335
36310
T228
V
T
I
S
H
R
Y
T
P
K
E
Q
L
K
M
Zebra Danio
Brachydanio rerio
NP_001002181
338
36917
T228
V
T
I
S
H
R
Y
T
P
K
E
Q
L
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q04448
309
33532
T206
V
T
I
C
H
R
Y
T
P
P
K
E
L
A
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793717
336
36041
Y227
T
V
T
L
C
H
R
Y
T
P
P
E
Q
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.7
56.5
90.3
N.A.
62.5
78.6
N.A.
59.1
62.6
64.1
63.6
N.A.
52
N.A.
N.A.
53.5
Protein Similarity:
100
75.9
57.1
92.2
N.A.
72.8
83.1
N.A.
71.6
74.7
76.7
75.4
N.A.
66
N.A.
N.A.
66.6
P-Site Identity:
100
100
100
100
N.A.
86.6
80
N.A.
13.3
86.6
86.6
80
N.A.
60
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
20
93.3
100
93.3
N.A.
73.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
42
0
0
0
0
0
0
0
9
0
9
9
% A
% Cys:
0
0
0
9
9
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
9
0
0
0
0
0
0
0
75
17
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
84
9
9
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
84
0
0
0
0
0
0
0
0
0
0
9
42
% I
% Lys:
0
0
0
0
0
0
0
0
0
67
9
0
0
67
9
% K
% Leu:
0
0
0
9
9
0
0
0
0
0
9
0
84
9
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
9
0
0
0
0
0
0
0
84
17
9
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
9
0
75
9
0
17
% Q
% Arg:
0
9
0
0
0
92
9
0
0
9
0
0
0
9
9
% R
% Ser:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
9
84
9
0
0
0
0
84
9
0
0
0
0
0
0
% T
% Val:
84
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
75
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _