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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF121
All Species:
25.45
Human Site:
S224
Identified Species:
80
UniProt:
Q9H920
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H920
NP_060790.2
327
37882
S224
P
T
K
H
L
S
D
S
V
C
A
V
C
G
Q
Chimpanzee
Pan troglodytes
XP_001174543
295
34507
S192
P
T
K
H
L
S
D
S
V
C
A
V
C
G
Q
Rhesus Macaque
Macaca mulatta
XP_001113850
327
37878
S224
P
T
K
H
L
S
D
S
V
C
A
V
C
G
Q
Dog
Lupus familis
XP_534023
327
37912
S224
P
T
K
H
L
S
D
S
V
C
A
V
C
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1Z9
327
37968
S224
P
T
K
H
L
S
D
S
V
C
A
V
C
G
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DD32
327
37920
S224
P
T
K
H
L
S
D
S
V
C
A
V
C
G
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09251
409
47609
G294
P
K
K
H
L
E
D
G
V
C
A
V
C
G
G
Sea Urchin
Strong. purpuratus
XP_001176116
331
38964
Y228
P
G
R
A
L
E
P
Y
I
C
A
V
C
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.2
99.6
99.3
N.A.
98.1
N.A.
N.A.
N.A.
N.A.
88.9
N.A.
N.A.
N.A.
N.A.
41.8
61.6
Protein Similarity:
100
90.2
100
99.6
N.A.
99
N.A.
N.A.
N.A.
N.A.
96.3
N.A.
N.A.
N.A.
N.A.
58.1
76.7
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
73.3
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
73.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
0
0
0
0
0
100
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
100
0
0
100
0
0
% C
% Asp:
0
0
0
0
0
0
88
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
13
0
0
0
0
0
13
0
0
0
0
0
100
13
% G
% His:
0
0
0
88
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% I
% Lys:
0
13
88
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
100
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
75
% Q
% Arg:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
75
0
75
0
0
0
0
0
0
0
% S
% Thr:
0
75
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
88
0
0
100
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _