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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF121 All Species: 22.73
Human Site: S286 Identified Species: 71.43
UniProt: Q9H920 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H920 NP_060790.2 327 37882 S286 V D L K R M F S N P W E R P H
Chimpanzee Pan troglodytes XP_001174543 295 34507 S254 V D L K R M F S N P W E R P H
Rhesus Macaque Macaca mulatta XP_001113850 327 37878 S286 V D L K R M F S N P W E R P H
Dog Lupus familis XP_534023 327 37912 S286 V D L K R M F S N P W E R P H
Cat Felis silvestris
Mouse Mus musculus Q8R1Z9 327 37968 S286 V D L K R M F S N P W E R P H
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6DD32 327 37920 S286 V D L K R M F S N P W E R P H
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09251 409 47609 K368 V D L Q R M F K N P W E K P H
Sea Urchin Strong. purpuratus XP_001176116 331 38964 K290 V D L K R M F K N P W E R P H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.2 99.6 99.3 N.A. 98.1 N.A. N.A. N.A. N.A. 88.9 N.A. N.A. N.A. N.A. 41.8 61.6
Protein Similarity: 100 90.2 100 99.6 N.A. 99 N.A. N.A. N.A. N.A. 96.3 N.A. N.A. N.A. N.A. 58.1 76.7
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. N.A. N.A. 100 N.A. N.A. N.A. N.A. 80 93.3
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. N.A. N.A. 100 N.A. N.A. N.A. N.A. 93.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % E
% Phe: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 88 0 0 0 25 0 0 0 0 13 0 0 % K
% Leu: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 100 0 0 0 100 0 % P
% Gln: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 100 0 0 0 0 0 0 0 88 0 0 % R
% Ser: 0 0 0 0 0 0 0 75 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _