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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A22 All Species: 23.03
Human Site: S255 Identified Species: 50.67
UniProt: Q9H936 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H936 NP_078974.1 323 34470 S255 V V K T R L Q S L Q R G V N E
Chimpanzee Pan troglodytes XP_001150398 268 28576 N206 Q S L Q R G V N E D T Y S G I
Rhesus Macaque Macaca mulatta XP_001087788 323 34516 S255 V V K T R L Q S L Q R G V N E
Dog Lupus familis XP_534936 332 35600 T268 V L K T R I Q T L K K G L G E
Cat Felis silvestris
Mouse Mus musculus Q9D6M3 323 34652 S255 V V K T R L Q S L E R G V N E
Rat Rattus norvegicus Q505J6 320 34152 T256 V L K T R I Q T L K K G L G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_427233 322 34755 S254 V I K T R L Q S L Q R G V N E
Frog Xenopus laevis Q6DE75 302 33153 A236 A S V A T Q P A D V I K T H M
Zebra Danio Brachydanio rerio Q6DHS9 309 34088 V243 V T A T P S D V V K S R L Q A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VA73 695 76736 S602 T A A R V F R S S P Q F G V T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q21153 707 78652 K612 D C A R K L I K E E G P M S L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82 98.7 62.9 N.A. 95.6 62.5 N.A. N.A. 83.9 22.9 26.6 N.A. 21 N.A. 20.5 N.A.
Protein Similarity: 100 82 99.6 75.3 N.A. 97.8 76.4 N.A. N.A. 91 39.9 43.6 N.A. 30.7 N.A. 31.8 N.A.
P-Site Identity: 100 6.6 100 53.3 N.A. 93.3 53.3 N.A. N.A. 93.3 0 13.3 N.A. 6.6 N.A. 6.6 N.A.
P-Site Similarity: 100 13.3 100 93.3 N.A. 100 93.3 N.A. N.A. 100 13.3 33.3 N.A. 20 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 28 10 0 0 0 10 0 0 0 0 0 0 10 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 10 0 10 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 19 19 0 0 0 0 55 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 10 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 10 55 10 28 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 10 0 0 0 19 10 0 0 0 10 0 0 0 10 % I
% Lys: 0 0 55 0 10 0 0 10 0 28 19 10 0 0 0 % K
% Leu: 0 19 10 0 0 46 0 0 55 0 0 0 28 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 0 0 37 0 % N
% Pro: 0 0 0 0 10 0 10 0 0 10 0 10 0 0 0 % P
% Gln: 10 0 0 10 0 10 55 0 0 28 10 0 0 10 0 % Q
% Arg: 0 0 0 19 64 0 10 0 0 0 37 10 0 0 0 % R
% Ser: 0 19 0 0 0 10 0 46 10 0 10 0 10 10 0 % S
% Thr: 10 10 0 64 10 0 0 19 0 0 10 0 10 0 10 % T
% Val: 64 28 10 0 10 0 10 10 10 10 0 0 37 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _