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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR76
All Species:
7.88
Human Site:
S135
Identified Species:
19.26
UniProt:
Q9H967
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H967
NP_079184.1
626
69753
S135
T
A
D
A
M
N
L
S
V
D
V
E
S
S
Q
Chimpanzee
Pan troglodytes
XP_523063
625
69588
S135
T
A
D
A
M
N
L
S
V
D
V
E
S
S
Q
Rhesus Macaque
Macaca mulatta
XP_001109470
625
69527
V135
A
D
A
M
N
L
S
V
D
V
E
S
S
Q
D
Dog
Lupus familis
XP_544653
631
70674
V137
H
K
S
T
S
D
T
V
I
L
R
E
V
D
R
Cat
Felis silvestris
Mouse
Mus musculus
A6PWY4
622
68989
S136
T
S
D
S
A
T
L
S
V
D
A
E
S
S
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519229
550
59965
R68
A
D
E
T
T
P
R
R
S
M
R
L
L
K
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4KLQ5
580
65709
P98
E
Y
H
T
E
T
M
P
T
P
K
K
N
Y
K
Zebra Danio
Brachydanio rerio
XP_698586
553
62257
R71
T
R
R
A
V
K
R
R
I
S
G
S
E
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797961
510
57218
E28
L
E
T
P
G
L
S
E
Y
E
K
R
R
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12510
522
59137
V40
Q
I
K
H
E
A
G
V
L
E
K
S
R
A
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
96.1
81.4
N.A.
71
N.A.
N.A.
45.2
N.A.
45.6
33.8
N.A.
N.A.
N.A.
N.A.
32.9
Protein Similarity:
100
98.8
97.9
87.3
N.A.
82.2
N.A.
N.A.
59.5
N.A.
62.2
54.9
N.A.
N.A.
N.A.
N.A.
49.5
P-Site Identity:
100
100
6.6
6.6
N.A.
60
N.A.
N.A.
0
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
6.6
26.6
N.A.
73.3
N.A.
N.A.
6.6
N.A.
26.6
33.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
20
10
30
10
10
0
0
0
0
10
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
30
0
0
10
0
0
10
30
0
0
0
10
20
% D
% Glu:
10
10
10
0
20
0
0
10
0
20
10
40
10
0
20
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
10
0
0
0
10
0
0
0
0
% G
% His:
10
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
20
0
0
0
0
0
0
% I
% Lys:
0
10
10
0
0
10
0
0
0
0
30
10
0
20
10
% K
% Leu:
10
0
0
0
0
20
30
0
10
10
0
10
10
10
0
% L
% Met:
0
0
0
10
20
0
10
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
20
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
10
0
10
0
10
0
10
0
0
0
0
10
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
20
% Q
% Arg:
0
10
10
0
0
0
20
20
0
0
20
10
20
0
10
% R
% Ser:
0
10
10
10
10
0
20
30
10
10
0
30
40
30
0
% S
% Thr:
40
0
10
30
10
20
10
0
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
30
30
10
20
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
10
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _