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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR54 All Species: 22.42
Human Site: S157 Identified Species: 44.85
UniProt: Q9H977 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H977 NP_115494.1 334 35891 S157 K G P N I V L S E E L A G H Q
Chimpanzee Pan troglodytes XP_001157952 334 35902 S157 K G P N I V L S E E L A G H Q
Rhesus Macaque Macaca mulatta XP_001108886 334 35784 S157 K G P N I V L S E E L A G H Q
Dog Lupus familis XP_532999 334 35613 S157 K G P N I V L S E E L A G H Q
Cat Felis silvestris
Mouse Mus musculus Q9R0D8 334 35594 S157 K G P N I V L S E E L A G H Q
Rat Rattus norvegicus NP_001102715 334 35576 N157 K G P N I V L N E E L A G H Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511568 202 21107 T32 A L P A R G L T R Y G V V H G
Chicken Gallus gallus XP_423570 290 30639 F120 H P P A Q A V F A R G I S A A
Frog Xenopus laevis NP_001090336 337 36126 A159 K G T N I T L A E V L A E H R
Zebra Danio Brachydanio rerio NP_001003630 336 36811 S159 K G S N I T L S E V L E E H K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_508163 347 38048 G163 I V V I M C N G D S N F S S R
Sea Urchin Strong. purpuratus XP_780149 334 35676 R157 L V F S I P S R G T N V Q L S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.1 89.5 N.A. 88.6 88.3 N.A. 34.7 53.5 60.5 55.9 N.A. N.A. N.A. 25.9 43.7
Protein Similarity: 100 100 99 94.6 N.A. 93.1 93.1 N.A. 43.7 63.4 75.3 72 N.A. N.A. N.A. 48.7 61.9
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. 20 6.6 60 60 N.A. N.A. N.A. 0 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 26.6 13.3 73.3 66.6 N.A. N.A. N.A. 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 17 0 9 0 9 9 0 0 59 0 9 9 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 67 50 0 9 17 0 0 % E
% Phe: 0 0 9 0 0 0 0 9 0 0 0 9 0 0 0 % F
% Gly: 0 67 0 0 0 9 0 9 9 0 17 0 50 0 9 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 0 0 75 0 % H
% Ile: 9 0 0 9 75 0 0 0 0 0 0 9 0 0 0 % I
% Lys: 67 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % K
% Leu: 9 9 0 0 0 0 75 0 0 0 67 0 0 9 0 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 67 0 0 9 9 0 0 17 0 0 0 0 % N
% Pro: 0 9 67 0 0 9 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 9 0 0 0 0 0 0 0 9 0 50 % Q
% Arg: 0 0 0 0 9 0 0 9 9 9 0 0 0 0 17 % R
% Ser: 0 0 9 9 0 0 9 50 0 9 0 0 17 9 9 % S
% Thr: 0 0 9 0 0 17 0 9 0 9 0 0 0 0 0 % T
% Val: 0 17 9 0 0 50 9 0 0 17 0 17 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _