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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR54
All Species:
24.85
Human Site:
S287
Identified Species:
49.7
UniProt:
Q9H977
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H977
NP_115494.1
334
35891
S287
K
L
S
R
N
P
E
S
G
Y
I
E
V
E
H
Chimpanzee
Pan troglodytes
XP_001157952
334
35902
S287
K
L
S
R
N
P
E
S
G
Y
I
E
V
E
H
Rhesus Macaque
Macaca mulatta
XP_001108886
334
35784
S287
K
L
S
R
S
P
E
S
G
Y
I
E
V
E
H
Dog
Lupus familis
XP_532999
334
35613
S287
K
L
S
R
S
P
E
S
G
H
T
E
V
E
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0D8
334
35594
S287
K
L
N
R
N
P
E
S
G
S
I
E
V
E
H
Rat
Rattus norvegicus
NP_001102715
334
35576
S287
K
L
N
R
N
P
E
S
G
S
I
E
V
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511568
202
21107
G156
R
R
R
P
R
G
G
G
D
R
Q
S
T
F
A
Chicken
Gallus gallus
XP_423570
290
30639
R244
E
A
A
T
G
S
L
R
A
Q
V
G
A
H
A
Frog
Xenopus laevis
NP_001090336
337
36126
C290
W
Q
L
S
R
S
D
C
G
T
I
E
V
E
H
Zebra Danio
Brachydanio rerio
NP_001003630
336
36811
T289
H
L
S
L
T
P
E
T
N
S
V
E
M
E
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_508163
347
38048
P292
S
K
L
H
T
R
K
P
H
A
Y
Q
V
E
Y
Sea Urchin
Strong. purpuratus
XP_780149
334
35676
Q287
S
L
K
A
D
D
N
Q
A
K
M
K
V
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.1
89.5
N.A.
88.6
88.3
N.A.
34.7
53.5
60.5
55.9
N.A.
N.A.
N.A.
25.9
43.7
Protein Similarity:
100
100
99
94.6
N.A.
93.1
93.1
N.A.
43.7
63.4
75.3
72
N.A.
N.A.
N.A.
48.7
61.9
P-Site Identity:
100
100
93.3
80
N.A.
86.6
86.6
N.A.
0
0
40
46.6
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
6.6
20
46.6
66.6
N.A.
N.A.
N.A.
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
9
0
0
0
0
17
9
0
0
9
0
17
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
9
9
0
9
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
59
0
0
0
0
67
0
75
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
0
0
9
9
9
9
59
0
0
9
0
0
0
% G
% His:
9
0
0
9
0
0
0
0
9
9
0
0
0
9
67
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% I
% Lys:
50
9
9
0
0
0
9
0
0
9
0
9
0
0
0
% K
% Leu:
0
67
17
9
0
0
9
0
0
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% M
% Asn:
0
0
17
0
34
0
9
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
59
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
9
0
9
9
9
0
0
0
% Q
% Arg:
9
9
9
50
17
9
0
9
0
9
0
0
0
0
0
% R
% Ser:
17
0
42
9
17
17
0
50
0
25
0
9
0
9
0
% S
% Thr:
0
0
0
9
17
0
0
9
0
9
9
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
17
0
75
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
25
9
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _