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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR54 All Species: 28.48
Human Site: T168 Identified Species: 56.97
UniProt: Q9H977 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H977 NP_115494.1 334 35891 T168 A G H Q M P I T D I A T E P A
Chimpanzee Pan troglodytes XP_001157952 334 35902 T168 A G H Q M P I T D I A T E P A
Rhesus Macaque Macaca mulatta XP_001108886 334 35784 T168 A G H Q T P I T D I A T E P A
Dog Lupus familis XP_532999 334 35613 T168 A G H Q T S V T D I A T E P A
Cat Felis silvestris
Mouse Mus musculus Q9R0D8 334 35594 T168 A G H Q T P I T D I A T E R A
Rat Rattus norvegicus NP_001102715 334 35576 T168 A G H Q T P I T D I A T E R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511568 202 21107 Q43 V V H G A A A Q L L S A T P D
Chicken Gallus gallus XP_423570 290 30639 F131 I S A A G E R F I C V G M S S
Frog Xenopus laevis NP_001090336 337 36126 T170 A E H R E P I T D I A S D S A
Zebra Danio Brachydanio rerio NP_001003630 336 36811 T170 E E H K E A I T D M A S E C S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_508163 347 38048 K174 F S S R K N L K E H R C A I T
Sea Urchin Strong. purpuratus XP_780149 334 35676 S168 V Q L S E T L S G H S Y P I S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.1 89.5 N.A. 88.6 88.3 N.A. 34.7 53.5 60.5 55.9 N.A. N.A. N.A. 25.9 43.7
Protein Similarity: 100 100 99 94.6 N.A. 93.1 93.1 N.A. 43.7 63.4 75.3 72 N.A. N.A. N.A. 48.7 61.9
P-Site Identity: 100 100 93.3 80 N.A. 86.6 86.6 N.A. 13.3 0 60 40 N.A. N.A. N.A. 0 0
P-Site Similarity: 100 100 93.3 86.6 N.A. 86.6 86.6 N.A. 26.6 6.6 80 66.6 N.A. N.A. N.A. 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 59 0 9 9 9 17 9 0 0 0 67 9 9 0 59 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 9 0 9 0 % C
% Asp: 0 0 0 0 0 0 0 0 67 0 0 0 9 0 9 % D
% Glu: 9 17 0 0 25 9 0 0 9 0 0 0 59 0 0 % E
% Phe: 9 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 0 50 0 9 9 0 0 0 9 0 0 9 0 0 0 % G
% His: 0 0 75 0 0 0 0 0 0 17 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 59 0 9 59 0 0 0 17 0 % I
% Lys: 0 0 0 9 9 0 0 9 0 0 0 0 0 0 0 % K
% Leu: 0 0 9 0 0 0 17 0 9 9 0 0 0 0 0 % L
% Met: 0 0 0 0 17 0 0 0 0 9 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 50 0 0 0 0 0 0 9 42 0 % P
% Gln: 0 9 0 50 0 0 0 9 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 17 0 0 9 0 0 0 9 0 0 17 0 % R
% Ser: 0 17 9 9 0 9 0 9 0 0 17 17 0 17 25 % S
% Thr: 0 0 0 0 34 9 0 67 0 0 0 50 9 0 9 % T
% Val: 17 9 0 0 0 0 9 0 0 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _