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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTR8 All Species: 19.7
Human Site: S459 Identified Species: 33.33
UniProt: Q9H981 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H981 NP_075050.3 624 70484 S459 E G D L R G Q S S D L P E R L
Chimpanzee Pan troglodytes XP_001173224 624 70505 S459 E G D L R G Q S S D L P E R L
Rhesus Macaque Macaca mulatta XP_001082127 624 70451 S459 E G D L R G Q S S D L P E R L
Dog Lupus familis XP_849247 624 70502 S459 E G D L R G Q S S D L P E R L
Cat Felis silvestris
Mouse Mus musculus Q8R2S9 624 70527 S459 E G D L R G Q S S D L P E R L
Rat Rattus norvegicus NP_001101866 148 16945 L18 S E E A L T A L M S R K T A I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519556 526 59431 A395 D S E E T P T A M M S R K T A
Chicken Gallus gallus XP_414336 622 70281 V457 E G D V R S Q V T D I S E R M
Frog Xenopus laevis NP_001080725 617 69712 I455 D E S R G Q D I S E R S H M Q
Zebra Danio Brachydanio rerio P59679 623 70114 E459 E G E S S V C E V S D R S S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VX09 607 67762 Q452 A G Y Q P R P Q L P V T A D D
Honey Bee Apis mellifera XP_394752 567 64044 N437 S A P I T L S N R D L D V P R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LSW2 596 66451 S462 M W D S F A F S P S K P K K E
Baker's Yeast Sacchar. cerevisiae Q12386 881 100191 A678 I L N R I L D A H N I I D Q L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.6 98.4 N.A. 97.1 23 N.A. 78.8 90.3 80.4 75.3 N.A. 32 40.3 N.A. N.A.
Protein Similarity: 100 99.8 99.8 99.5 N.A. 98.8 23.7 N.A. 81.4 95.5 89.4 87.6 N.A. 52.8 60 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 0 53.3 6.6 20 N.A. 6.6 13.3 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 26.6 80 20 26.6 N.A. 13.3 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.8 21.1 N.A.
Protein Similarity: N.A. N.A. N.A. 42.1 38 N.A.
P-Site Identity: N.A. N.A. N.A. 20 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 8 0 8 8 15 0 0 0 0 8 8 8 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 15 0 50 0 0 0 15 0 0 50 8 8 8 8 8 % D
% Glu: 50 15 22 8 0 0 0 8 0 8 0 0 43 0 8 % E
% Phe: 0 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 58 0 0 8 36 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % H
% Ile: 8 0 0 8 8 0 0 8 0 0 15 8 0 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 8 8 15 8 0 % K
% Leu: 0 8 0 36 8 15 0 8 8 0 43 0 0 0 50 % L
% Met: 8 0 0 0 0 0 0 0 15 8 0 0 0 8 8 % M
% Asn: 0 0 8 0 0 0 0 8 0 8 0 0 0 0 0 % N
% Pro: 0 0 8 0 8 8 8 0 8 8 0 43 0 8 0 % P
% Gln: 0 0 0 8 0 8 43 8 0 0 0 0 0 8 8 % Q
% Arg: 0 0 0 15 43 8 0 0 8 0 15 15 0 43 8 % R
% Ser: 15 8 8 15 8 8 8 43 43 22 8 15 8 8 0 % S
% Thr: 0 0 0 0 15 8 8 0 8 0 0 8 8 8 0 % T
% Val: 0 0 0 8 0 8 0 8 8 0 8 0 8 0 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _