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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC40
All Species:
11.21
Human Site:
S377
Identified Species:
15.42
UniProt:
Q9H9A6
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9A6
NP_060238.3
602
68250
S377
K
D
D
G
P
S
Q
S
E
S
A
T
E
T
A
Chimpanzee
Pan troglodytes
XP_513483
602
68201
S377
K
D
D
G
P
S
Q
S
E
S
A
T
E
T
A
Rhesus Macaque
Macaca mulatta
XP_001097485
602
68282
S377
K
D
D
G
P
S
Q
S
E
S
A
A
E
T
A
Dog
Lupus familis
XP_547338
555
63218
N347
L
P
S
E
S
R
V
N
V
H
A
I
I
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CRC8
602
68057
N377
K
D
D
R
T
N
Q
N
D
S
V
P
E
T
A
Rat
Rattus norvegicus
Q6AYI5
582
64902
I370
E
H
N
R
I
N
K
I
P
F
G
I
F
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505628
569
64113
T347
P
P
Q
N
E
T
T
T
T
G
T
A
M
T
L
Chicken
Gallus gallus
Q5ZLN0
603
67457
N378
Q
D
D
K
A
S
P
N
E
E
P
P
V
T
A
Frog
Xenopus laevis
Q6GPJ5
605
67086
A380
P
D
M
T
T
Q
E
A
A
N
P
P
D
T
A
Zebra Danio
Brachydanio rerio
Q7SXW3
601
67297
L376
Q
E
P
P
N
G
G
L
K
E
E
P
K
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEK6
641
69354
F414
P
T
G
G
P
A
Q
F
T
N
V
Y
S
I
N
Honey Bee
Apis mellifera
XP_395550
602
68893
K380
K
S
T
N
L
D
S
K
K
H
V
T
L
N
T
Nematode Worm
Caenorhab. elegans
Q22875
559
62465
T352
I
G
I
F
S
K
A
T
R
L
T
K
L
N
L
Sea Urchin
Strong. purpuratus
XP_797039
713
79157
P389
R
S
R
I
E
E
T
P
E
D
T
P
D
S
S
Poplar Tree
Populus trichocarpa
XP_002316909
580
63311
E362
R
L
S
V
S
S
K
E
L
S
L
Q
G
L
G
Maize
Zea mays
NP_001169465
584
63651
K361
R
R
L
S
L
S
S
K
E
L
D
L
S
G
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZG8
1045
115404
T689
L
C
G
S
V
N
T
T
Q
G
L
K
P
C
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.5
83.7
N.A.
83
26
N.A.
74
70.1
62.8
62.4
N.A.
24.3
36.5
23.2
38.1
Protein Similarity:
100
99.8
99
88.2
N.A.
91.5
45.5
N.A.
84.3
83.5
79
79
N.A.
43.8
56.9
47.8
59.8
P-Site Identity:
100
100
93.3
13.3
N.A.
53.3
0
N.A.
6.6
40
20
13.3
N.A.
20
13.3
0
6.6
P-Site Similarity:
100
100
93.3
20
N.A.
73.3
33.3
N.A.
20
53.3
46.6
40
N.A.
33.3
20
6.6
33.3
Percent
Protein Identity:
32.3
33
N.A.
22.3
N.A.
N.A.
Protein Similarity:
53.6
52.8
N.A.
35.8
N.A.
N.A.
P-Site Identity:
13.3
13.3
N.A.
0
N.A.
N.A.
P-Site Similarity:
26.6
20
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
6
6
6
6
6
0
24
12
0
0
42
% A
% Cys:
0
6
0
0
0
0
0
0
0
0
0
0
0
6
0
% C
% Asp:
0
36
30
0
0
6
0
0
6
6
6
0
12
0
0
% D
% Glu:
6
6
0
6
12
6
6
6
36
12
6
0
24
0
0
% E
% Phe:
0
0
0
6
0
0
0
6
0
6
0
0
6
0
0
% F
% Gly:
0
6
12
24
0
6
6
0
0
12
6
0
6
6
6
% G
% His:
0
6
0
0
0
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
6
0
6
6
6
0
0
6
0
0
0
12
6
6
0
% I
% Lys:
30
0
0
6
0
6
12
12
12
0
0
12
6
0
0
% K
% Leu:
12
6
6
0
12
0
0
6
6
12
12
6
12
6
24
% L
% Met:
0
0
6
0
0
0
0
0
0
0
0
0
6
0
0
% M
% Asn:
0
0
6
12
6
18
0
18
0
12
0
0
0
12
6
% N
% Pro:
18
12
6
6
24
0
6
6
6
0
12
30
6
0
0
% P
% Gln:
12
0
6
0
0
6
30
0
6
0
0
6
0
0
0
% Q
% Arg:
18
6
6
12
0
6
0
0
6
0
0
0
0
0
6
% R
% Ser:
0
12
12
12
18
36
12
18
0
30
0
0
12
12
12
% S
% Thr:
0
6
6
6
12
6
18
18
12
0
18
18
0
53
6
% T
% Val:
0
0
0
6
6
0
6
0
6
0
18
0
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _