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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LRRC40 All Species: 23.33
Human Site: S457 Identified Species: 32.08
UniProt: Q9H9A6 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H9A6 NP_060238.3 602 68250 S457 M V S D V D L S F N K L S F I
Chimpanzee Pan troglodytes XP_513483 602 68201 S457 M V S D V D L S F N K L S F I
Rhesus Macaque Macaca mulatta XP_001097485 602 68282 S457 M V S D V N L S F N K L S F I
Dog Lupus familis XP_547338 555 63218 M423 F I S L E L C M L Q K L T F L
Cat Felis silvestris
Mouse Mus musculus Q9CRC8 602 68057 S457 M V L D I N L S F N K L S F I
Rat Rattus norvegicus Q6AYI5 582 64902 N446 K L P H G L G N L R K L R E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505628 569 64113 S424 T V S D V N L S F N K L S L I
Chicken Gallus gallus Q5ZLN0 603 67457 G458 S V C D V N F G F N K I S S V
Frog Xenopus laevis Q6GPJ5 605 67086 G460 S V Y D V N L G F N K I S S I
Zebra Danio Brachydanio rerio Q7SXW3 601 67297 G456 S L A D I N L G F N K L T T I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VEK6 641 69354 S493 N L E I L I L S N N M L K K I
Honey Bee Apis mellifera XP_395550 602 68893 S457 V A D L K L T S N Q L T H I P
Nematode Worm Caenorhab. elegans Q22875 559 62465 L428 N K L R E L D L E E N E L E T
Sea Urchin Strong. purpuratus XP_797039 713 79157 S568 T A V D V N L S V N K I P T L
Poplar Tree Populus trichocarpa XP_002316909 580 63311 S441 N A L T Q I P S D G F Q A V P
Maize Zea mays NP_001169465 584 63651 N437 L S S L K L D N N P L V E I S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VZG8 1045 115404 M799 A K L P N A I M A V K K L N E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 97.5 83.7 N.A. 83 26 N.A. 74 70.1 62.8 62.4 N.A. 24.3 36.5 23.2 38.1
Protein Similarity: 100 99.8 99 88.2 N.A. 91.5 45.5 N.A. 84.3 83.5 79 79 N.A. 43.8 56.9 47.8 59.8
P-Site Identity: 100 100 93.3 26.6 N.A. 80 13.3 N.A. 80 46.6 60 46.6 N.A. 33.3 6.6 0 40
P-Site Similarity: 100 100 100 46.6 N.A. 93.3 33.3 N.A. 86.6 66.6 73.3 80 N.A. 46.6 13.3 0 60
Percent
Protein Identity: 32.3 33 N.A. 22.3 N.A. N.A.
Protein Similarity: 53.6 52.8 N.A. 35.8 N.A. N.A.
P-Site Identity: 6.6 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 26.6 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 18 6 0 0 6 0 0 6 0 0 0 6 0 0 % A
% Cys: 0 0 6 0 0 0 6 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 6 53 0 12 12 0 6 0 0 0 0 0 0 % D
% Glu: 0 0 6 0 12 0 0 0 6 6 0 6 6 12 6 % E
% Phe: 6 0 0 0 0 0 6 0 48 0 6 0 0 30 0 % F
% Gly: 0 0 0 0 6 0 6 18 0 6 0 0 0 0 0 % G
% His: 0 0 0 6 0 0 0 0 0 0 0 0 6 0 0 % H
% Ile: 0 6 0 6 12 12 6 0 0 0 0 18 0 12 48 % I
% Lys: 6 12 0 0 12 0 0 0 0 0 71 6 6 6 0 % K
% Leu: 6 18 24 18 6 30 53 6 12 0 12 53 12 6 18 % L
% Met: 24 0 0 0 0 0 0 12 0 0 6 0 0 0 0 % M
% Asn: 18 0 0 0 6 42 0 12 18 59 6 0 0 6 0 % N
% Pro: 0 0 6 6 0 0 6 0 0 6 0 0 6 0 12 % P
% Gln: 0 0 0 0 6 0 0 0 0 12 0 6 0 0 0 % Q
% Arg: 0 0 0 6 0 0 0 0 0 6 0 0 6 0 0 % R
% Ser: 18 6 36 0 0 0 0 53 0 0 0 0 42 12 6 % S
% Thr: 12 0 0 6 0 0 6 0 0 0 0 6 12 12 6 % T
% Val: 6 42 6 0 42 0 0 0 6 6 0 6 0 6 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _