KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EHMT1
All Species:
13.33
Human Site:
S404
Identified Species:
36.67
UniProt:
Q9H9B1
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9B1
NP_001138999.1
1267
138254
S404
K
R
K
G
K
T
D
S
P
W
I
K
P
A
R
Chimpanzee
Pan troglodytes
XP_520395
1499
164011
S636
K
R
K
G
K
T
D
S
P
W
I
K
P
A
R
Rhesus Macaque
Macaca mulatta
XP_001117637
1311
143552
I401
E
C
Q
P
E
S
S
I
S
H
R
F
H
K
D
Dog
Lupus familis
XP_848228
1265
138176
S403
K
R
K
G
K
P
D
S
P
W
I
K
P
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z148
1263
138021
K394
S
G
S
S
G
R
R
K
A
K
K
K
W
R
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509394
1282
141003
S405
K
R
K
G
K
T
D
S
P
W
I
K
P
S
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396833
1265
141508
R434
F
L
K
P
A
A
G
R
P
K
R
E
R
G
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785941
548
61937
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82175
794
88134
I20
R
G
G
D
G
G
G
I
P
C
S
K
D
E
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.4
80.8
89.7
N.A.
45.5
N.A.
N.A.
78
N.A.
N.A.
N.A.
N.A.
N.A.
33.2
N.A.
24.7
Protein Similarity:
100
78.7
81.8
94.1
N.A.
60.8
N.A.
N.A.
85.5
N.A.
N.A.
N.A.
N.A.
N.A.
51.5
N.A.
33.8
P-Site Identity:
100
100
0
93.3
N.A.
6.6
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
0
P-Site Similarity:
100
100
26.6
93.3
N.A.
13.3
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
12
0
0
12
0
0
0
0
34
0
% A
% Cys:
0
12
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
0
45
0
0
0
0
0
12
0
12
% D
% Glu:
12
0
0
0
12
0
0
0
0
0
0
12
0
12
0
% E
% Phe:
12
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% F
% Gly:
0
23
12
45
23
12
23
0
0
0
0
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
12
0
0
12
0
0
% H
% Ile:
0
0
0
0
0
0
0
23
0
0
45
0
0
0
0
% I
% Lys:
45
0
56
0
45
0
0
12
0
23
12
67
0
12
12
% K
% Leu:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
23
0
12
0
0
67
0
0
0
45
0
0
% P
% Gln:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
45
0
0
0
12
12
12
0
0
23
0
12
12
56
% R
% Ser:
12
0
12
12
0
12
12
45
12
0
12
0
0
12
0
% S
% Thr:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
45
0
0
12
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _