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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFXN1
All Species:
8.79
Human Site:
S46
Identified Species:
16.11
UniProt:
Q9H9B4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9B4
NP_073591.2
322
35619
S46
L
T
N
E
Q
L
E
S
A
R
K
I
V
H
D
Chimpanzee
Pan troglodytes
XP_001156380
322
35629
S46
L
T
N
E
Q
L
E
S
A
R
K
I
V
H
D
Rhesus Macaque
Macaca mulatta
XP_001082798
322
35633
S46
L
T
N
E
Q
L
E
S
A
R
K
I
V
R
D
Dog
Lupus familis
XP_546226
298
32736
W45
G
L
T
E
N
E
L
W
R
A
K
Y
I
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
Q99JR1
322
35631
N46
L
T
N
E
Q
L
E
N
A
R
K
V
V
H
D
Rat
Rattus norvegicus
Q63965
322
35528
N46
L
T
N
E
Q
L
E
N
A
R
K
V
V
H
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511523
322
35745
K46
L
T
N
E
Q
L
E
K
A
R
Q
I
V
H
D
Chicken
Gallus gallus
XP_414544
322
35657
N46
L
S
D
A
Q
L
E
N
A
R
K
I
V
H
D
Frog
Xenopus laevis
NP_001090349
322
35633
R46
L
P
N
D
Q
L
E
R
S
R
Q
I
V
H
D
Zebra Danio
Brachydanio rerio
NP_001003537
322
35475
K46
L
S
N
K
Q
L
E
K
A
H
Q
I
I
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09201
329
36736
K49
S
S
R
I
Q
Q
E
K
C
K
E
I
V
T
N
Sea Urchin
Strong. purpuratus
XP_794780
334
36713
E58
L
S
N
A
Q
L
D
E
A
K
K
L
V
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12029
327
35396
L44
L
L
T
T
E
K
D
L
A
H
A
R
E
I
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99
85.7
N.A.
94.7
95
N.A.
90.3
90.9
91.3
84.1
N.A.
N.A.
N.A.
47.7
64.3
Protein Similarity:
100
99.6
99.6
88.8
N.A.
96.8
97.5
N.A.
95.3
96.5
95.6
92.5
N.A.
N.A.
N.A.
64.4
76.9
P-Site Identity:
100
100
93.3
20
N.A.
86.6
86.6
N.A.
86.6
73.3
66.6
53.3
N.A.
N.A.
N.A.
26.6
46.6
P-Site Similarity:
100
100
93.3
33.3
N.A.
100
100
N.A.
93.3
93.3
86.6
80
N.A.
N.A.
N.A.
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
0
0
0
0
77
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
16
0
0
0
0
0
0
0
77
% D
% Glu:
0
0
0
54
8
8
77
8
0
0
8
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
16
0
0
0
54
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
62
16
8
8
% I
% Lys:
0
0
0
8
0
8
0
24
0
16
62
0
0
0
0
% K
% Leu:
85
16
0
0
0
77
8
8
0
0
0
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
70
0
8
0
0
24
0
0
0
0
0
0
8
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
85
8
0
0
0
0
24
0
0
16
0
% Q
% Arg:
0
0
8
0
0
0
0
8
8
62
0
8
0
8
0
% R
% Ser:
8
31
0
0
0
0
0
24
8
0
0
0
0
0
0
% S
% Thr:
0
47
16
8
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
16
77
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _