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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF408 All Species: 9.09
Human Site: S113 Identified Species: 28.57
UniProt: Q9H9D4 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H9D4 NP_079017.1 720 78439 S113 P R Q E E N L S L G P W G D V
Chimpanzee Pan troglodytes A2T759 682 76399 F76 T R T E D K E F L H K E D I H
Rhesus Macaque Macaca mulatta XP_001111210 719 78520 S113 P R Q E E N L S L G P W G D M
Dog Lupus familis XP_540750 752 82813 S135 P R R K E D V S L G P W G D V
Cat Felis silvestris
Mouse Mus musculus Q80W31 679 77298 V96 Q K I Q D G Q V F E G I V V T
Rat Rattus norvegicus XP_002726662 458 53076
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis P18729 336 37535
Zebra Danio Brachydanio rerio XP_001333167 764 85982 K82 N A S Q S V Y K R E I S D E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.9 94.5 78.9 N.A. 23.3 26.3 N.A. N.A. N.A. 20.8 39.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 37.7 96.1 84.7 N.A. 38.7 37.7 N.A. N.A. N.A. 31.1 53.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 93.3 73.3 N.A. 0 0 N.A. N.A. N.A. 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 20 0 N.A. N.A. N.A. 0 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 25 13 0 0 0 0 0 0 25 38 0 % D
% Glu: 0 0 0 38 38 0 13 0 0 25 0 13 0 13 0 % E
% Phe: 0 0 0 0 0 0 0 13 13 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 13 0 0 0 38 13 0 38 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 13 % H
% Ile: 0 0 13 0 0 0 0 0 0 0 13 13 0 13 0 % I
% Lys: 0 13 0 13 0 13 0 13 0 0 13 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 25 0 50 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % M
% Asn: 13 0 0 0 0 25 0 0 0 0 0 0 0 0 0 % N
% Pro: 38 0 0 0 0 0 0 0 0 0 38 0 0 0 0 % P
% Gln: 13 0 25 25 0 0 13 0 0 0 0 0 0 0 0 % Q
% Arg: 0 50 13 0 0 0 0 0 13 0 0 0 0 0 0 % R
% Ser: 0 0 13 0 13 0 0 38 0 0 0 13 0 0 0 % S
% Thr: 13 0 13 0 0 0 0 0 0 0 0 0 0 0 13 % T
% Val: 0 0 0 0 0 13 13 13 0 0 0 0 13 13 38 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 38 0 0 0 % W
% Tyr: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _