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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF408
All Species:
15.15
Human Site:
S545
Identified Species:
47.62
UniProt:
Q9H9D4
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9D4
NP_079017.1
720
78439
S545
E
L
R
R
H
L
I
S
H
T
G
E
A
H
L
Chimpanzee
Pan troglodytes
A2T759
682
76399
V510
A
L
I
Q
H
Q
G
V
H
T
G
D
K
P
Y
Rhesus Macaque
Macaca mulatta
XP_001111210
719
78520
S544
E
L
R
R
H
L
I
S
H
T
G
E
A
H
L
Dog
Lupus familis
XP_540750
752
82813
S573
E
L
R
R
H
L
I
S
H
T
G
E
A
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80W31
679
77298
T504
S
Q
K
Q
N
F
I
T
H
Q
K
V
H
T
G
Rat
Rattus norvegicus
XP_002726662
458
53076
K296
Y
K
C
N
Q
C
D
K
A
F
A
Q
H
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
P18729
336
37535
F174
I
H
T
G
E
K
P
F
T
C
T
E
C
G
D
Zebra Danio
Brachydanio rerio
XP_001333167
764
85982
S517
E
L
R
R
H
L
I
S
H
T
G
E
V
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.9
94.5
78.9
N.A.
23.3
26.3
N.A.
N.A.
N.A.
20.8
39.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
37.7
96.1
84.7
N.A.
38.7
37.7
N.A.
N.A.
N.A.
31.1
53.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
100
93.3
N.A.
13.3
0
N.A.
N.A.
N.A.
6.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
100
100
N.A.
40
6.6
N.A.
N.A.
N.A.
6.6
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
0
0
0
0
13
0
13
0
38
0
0
% A
% Cys:
0
0
13
0
0
13
0
0
0
13
0
0
13
0
0
% C
% Asp:
0
0
0
0
0
0
13
0
0
0
0
13
0
0
13
% D
% Glu:
50
0
0
0
13
0
0
0
0
0
0
63
0
0
0
% E
% Phe:
0
0
0
0
0
13
0
13
0
13
0
0
0
0
0
% F
% Gly:
0
0
0
13
0
0
13
0
0
0
63
0
0
13
13
% G
% His:
0
13
0
0
63
0
0
0
75
0
0
0
25
25
0
% H
% Ile:
13
0
13
0
0
0
63
0
0
0
0
0
0
0
0
% I
% Lys:
0
13
13
0
0
13
0
13
0
0
13
0
13
0
0
% K
% Leu:
0
63
0
0
0
50
0
0
0
0
0
0
0
0
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
13
13
0
0
0
0
0
0
0
0
0
13
% N
% Pro:
0
0
0
0
0
0
13
0
0
0
0
0
0
13
0
% P
% Gln:
0
13
0
25
13
13
0
0
0
13
0
13
0
0
0
% Q
% Arg:
0
0
50
50
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
13
0
0
0
0
0
0
50
0
0
0
0
0
13
0
% S
% Thr:
0
0
13
0
0
0
0
13
13
63
13
0
0
13
0
% T
% Val:
0
0
0
0
0
0
0
13
0
0
0
13
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
0
0
0
0
0
0
0
0
0
0
25
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _