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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG4
All Species:
26.97
Human Site:
S543
Identified Species:
49.44
UniProt:
Q9H9E3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9E3
NP_056201.2
785
89095
S543
S
T
D
E
A
K
M
S
F
L
V
T
L
N
N
Chimpanzee
Pan troglodytes
XP_511080
790
89810
S548
S
T
D
E
A
K
M
S
F
L
V
T
L
N
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546836
788
89405
S546
S
T
D
E
A
K
L
S
F
L
V
T
L
N
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1U1
785
88642
S543
S
T
D
E
A
K
L
S
F
L
V
T
L
N
N
Rat
Rattus norvegicus
NP_001101919
785
88584
S543
S
T
D
E
A
K
L
S
F
L
V
T
L
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506619
778
88360
S536
S
T
D
E
A
K
L
S
F
L
V
T
L
N
N
Chicken
Gallus gallus
NP_001012793
771
87570
S529
S
T
D
E
A
K
Q
S
F
L
V
T
L
N
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001034912
781
87569
A539
S
Q
E
Q
A
K
S
A
Y
L
V
T
L
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95TN4
776
87696
N541
N
F
L
V
Q
L
N
N
A
D
I
S
T
E
Y
Honey Bee
Apis mellifera
XP_394599
741
84404
L508
R
L
T
F
L
A
Y
L
N
N
T
D
V
S
I
Nematode Worm
Caenorhab. elegans
Q95XZ0
801
91001
A556
P
V
K
E
A
A
D
A
Q
K
E
Q
F
L
L
Sea Urchin
Strong. purpuratus
XP_001204443
753
84933
L518
K
L
E
F
L
T
T
L
N
N
V
E
V
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L838
738
82959
E501
G
V
E
N
T
G
T
E
I
A
T
A
L
N
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
N.A.
96.8
N.A.
94.5
94.9
N.A.
90.1
84.5
N.A.
71.8
N.A.
40
45.4
31.2
57.7
Protein Similarity:
100
96.3
N.A.
97.9
N.A.
97.7
97.8
N.A.
95.4
91.4
N.A.
85.7
N.A.
62.7
66.6
54.8
73.5
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
60
N.A.
0
0
13.3
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
93.3
N.A.
86.6
N.A.
26.6
13.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
70
16
0
16
8
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
54
0
0
0
8
0
0
8
0
8
0
0
0
% D
% Glu:
0
0
24
62
0
0
0
8
0
0
8
8
0
8
0
% E
% Phe:
0
8
0
16
0
0
0
0
54
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
16
% I
% Lys:
8
0
8
0
0
62
0
0
0
8
0
0
0
0
0
% K
% Leu:
0
16
8
0
16
8
31
16
0
62
0
0
70
8
8
% L
% Met:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
8
8
16
16
0
0
0
70
70
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
8
8
0
8
0
8
0
0
8
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
62
0
0
0
0
0
8
54
0
0
0
8
0
16
0
% S
% Thr:
0
54
8
0
8
8
16
0
0
0
16
62
8
0
0
% T
% Val:
0
16
0
8
0
0
0
0
0
0
70
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _