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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COG4 All Species: 39.39
Human Site: Y151 Identified Species: 72.22
UniProt: Q9H9E3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H9E3 NP_056201.2 785 89095 Y151 T A L R S E D Y E Q A A A H I
Chimpanzee Pan troglodytes XP_511080 790 89810 Y156 T A L R N E D Y E Q A A A H I
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_546836 788 89405 Y154 T A L R N E D Y E Q A A A H I
Cat Felis silvestris
Mouse Mus musculus Q8R1U1 785 88642 Y151 T A L R N E D Y E Q A A A H I
Rat Rattus norvegicus NP_001101919 785 88584 Y151 T A L R S E D Y E Q A A A H I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506619 778 88360 Y144 T A L R N E D Y E Q A A A H I
Chicken Gallus gallus NP_001012793 771 87570 Y137 T A L R N E D Y E Q A A A H I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001034912 781 87569 Y143 T A L R N Q D Y E Q A A A H I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95TN4 776 87696 F137 S A T H I A R F L A M D Q Q L
Honey Bee Apis mellifera XP_394599 741 84404 E138 S M D Q Q L L E R T A E D I L
Nematode Worm Caenorhab. elegans Q95XZ0 801 91001 F159 D A I R S E D F E T A S Q H I
Sea Urchin Strong. purpuratus XP_001204443 753 84933 Y132 T A L Q S E D Y E K A A G H I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L838 738 82959 Y148 T A L E S E D Y E S A A K F V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.6 N.A. 96.8 N.A. 94.5 94.9 N.A. 90.1 84.5 N.A. 71.8 N.A. 40 45.4 31.2 57.7
Protein Similarity: 100 96.3 N.A. 97.9 N.A. 97.7 97.8 N.A. 95.4 91.4 N.A. 85.7 N.A. 62.7 66.6 54.8 73.5
P-Site Identity: 100 93.3 N.A. 93.3 N.A. 93.3 100 N.A. 93.3 93.3 N.A. 86.6 N.A. 6.6 6.6 60 80
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 N.A. 100 N.A. 26.6 26.6 80 93.3
Percent
Protein Identity: N.A. N.A. N.A. 33.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 56.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 66.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 93 0 0 0 8 0 0 0 8 93 77 62 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 0 0 0 85 0 0 0 0 8 8 0 0 % D
% Glu: 0 0 0 8 0 77 0 8 85 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 16 0 0 0 0 0 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 77 0 % H
% Ile: 0 0 8 0 8 0 0 0 0 0 0 0 0 8 77 % I
% Lys: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % K
% Leu: 0 0 77 0 0 8 8 0 8 0 0 0 0 0 16 % L
% Met: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 47 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 16 8 8 0 0 0 62 0 0 16 8 0 % Q
% Arg: 0 0 0 70 0 0 8 0 8 0 0 0 0 0 0 % R
% Ser: 16 0 0 0 39 0 0 0 0 8 0 8 0 0 0 % S
% Thr: 77 0 8 0 0 0 0 0 0 16 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 77 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _