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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG4
All Species:
19.7
Human Site:
Y46
Identified Species:
36.11
UniProt:
Q9H9E3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9E3
NP_056201.2
785
89095
Y46
L
Q
E
L
E
A
V
Y
E
R
L
C
G
E
E
Chimpanzee
Pan troglodytes
XP_511080
790
89810
Y46
L
Q
E
L
E
A
V
Y
E
R
L
C
G
E
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546836
788
89405
Y49
L
Q
E
L
E
A
V
Y
E
R
L
C
G
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1U1
785
88642
Y46
L
Q
E
L
E
A
V
Y
E
R
L
C
G
E
E
Rat
Rattus norvegicus
NP_001101919
785
88584
Y46
L
Q
E
L
E
A
V
Y
E
R
L
C
G
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506619
778
88360
E46
Y
E
R
L
C
D
E
E
K
A
V
E
K
E
L
Chicken
Gallus gallus
NP_001012793
771
87570
L46
E
N
A
V
Q
Q
E
L
D
A
L
L
E
Q
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001034912
781
87569
A46
A
Q
L
C
A
E
E
A
E
V
Q
V
E
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95TN4
776
87696
I46
L
L
A
K
Q
C
Q
I
E
A
K
M
S
G
I
Honey Bee
Apis mellifera
XP_394599
741
84404
P50
Q
N
I
S
K
V
L
P
N
V
V
V
I
R
T
Nematode Worm
Caenorhab. elegans
Q95XZ0
801
91001
E56
L
E
I
K
K
R
E
E
E
R
I
E
K
D
I
Sea Urchin
Strong. purpuratus
XP_001204443
753
84933
H47
E
I
D
L
L
L
D
H
H
G
H
L
E
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L838
738
82959
Y49
L
L
H
E
C
I
A
Y
Q
R
S
L
D
S
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
N.A.
96.8
N.A.
94.5
94.9
N.A.
90.1
84.5
N.A.
71.8
N.A.
40
45.4
31.2
57.7
Protein Similarity:
100
96.3
N.A.
97.9
N.A.
97.7
97.8
N.A.
95.4
91.4
N.A.
85.7
N.A.
62.7
66.6
54.8
73.5
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
13.3
6.6
N.A.
13.3
N.A.
13.3
0
20
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
33.3
40
N.A.
20
N.A.
20
20
46.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
0
8
39
8
8
0
24
0
0
0
8
0
% A
% Cys:
0
0
0
8
16
8
0
0
0
0
0
39
0
0
0
% C
% Asp:
0
0
8
0
0
8
8
0
8
0
0
0
8
8
16
% D
% Glu:
16
16
39
8
39
8
31
16
62
0
0
16
24
47
39
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
0
39
8
0
% G
% His:
0
0
8
0
0
0
0
8
8
0
8
0
0
0
0
% H
% Ile:
0
8
16
0
0
8
0
8
0
0
8
0
8
0
16
% I
% Lys:
0
0
0
16
16
0
0
0
8
0
8
0
16
0
8
% K
% Leu:
62
16
8
54
8
8
8
8
0
0
47
24
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
16
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
8
47
0
0
16
8
8
0
8
0
8
0
0
8
8
% Q
% Arg:
0
0
8
0
0
8
0
0
0
54
0
0
0
8
0
% R
% Ser:
0
0
0
8
0
0
0
0
0
0
8
0
8
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% T
% Val:
0
0
0
8
0
8
39
0
0
16
16
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _