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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTR5
All Species:
23.03
Human Site:
S281
Identified Species:
38.97
UniProt:
Q9H9F9
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9F9
NP_079131.3
607
68297
S281
H
K
M
Q
L
P
F
S
S
K
L
L
G
S
T
Chimpanzee
Pan troglodytes
XP_001145158
607
68237
S281
H
K
M
Q
L
P
F
S
S
K
L
L
G
S
T
Rhesus Macaque
Macaca mulatta
XP_001089026
607
68253
S281
H
K
M
Q
L
P
F
S
S
K
L
L
G
S
T
Dog
Lupus familis
XP_534418
363
41163
V89
H
L
G
V
S
S
Q
V
A
Y
G
I
D
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80US4
605
67941
S281
H
K
M
Q
L
P
F
S
S
K
L
L
G
S
T
Rat
Rattus norvegicus
NP_001102070
330
37120
E56
P
G
P
D
P
G
P
E
P
R
L
Q
F
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515798
283
31357
G9
A
L
D
K
G
E
Q
G
Q
V
R
R
P
A
S
Chicken
Gallus gallus
Q5ZJA4
611
69335
S283
H
K
M
Q
L
P
F
S
N
K
L
L
G
S
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998653
592
66401
S282
H
R
V
Q
L
P
F
S
G
R
S
A
G
V
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEC3
648
75103
N267
M
K
I
Q
L
P
Y
N
A
V
T
A
T
N
A
Honey Bee
Apis mellifera
XP_623919
674
77387
V271
L
R
V
Q
L
P
Y
V
A
P
A
N
A
P
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784230
560
63388
V284
P
E
Y
F
Q
K
H
V
H
K
I
Q
L
P
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q940Z2
590
67861
K270
T
P
E
Q
L
K
D
K
K
R
Q
M
F
L
K
Baker's Yeast
Sacchar. cerevisiae
P53946
755
87542
T282
V
V
V
E
A
P
F
T
E
V
L
Q
P
Q
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.5
56.6
N.A.
88.8
50.5
N.A.
34.9
78.7
N.A.
56.5
N.A.
28.8
41.5
N.A.
41.8
Protein Similarity:
100
100
99.1
58.6
N.A.
94
51.7
N.A.
40.8
86.5
N.A.
73.4
N.A.
49
59.5
N.A.
61.7
P-Site Identity:
100
100
100
13.3
N.A.
100
6.6
N.A.
0
93.3
N.A.
46.6
N.A.
26.6
20
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
13.3
N.A.
20
100
N.A.
66.6
N.A.
60
46.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
25
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.2
42.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
0
0
22
0
8
15
8
8
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
8
8
0
0
8
0
0
0
0
0
8
0
0
% D
% Glu:
0
8
8
8
0
8
0
8
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
50
0
0
0
0
0
15
0
0
% F
% Gly:
0
8
8
0
8
8
0
8
8
0
8
0
43
0
8
% G
% His:
50
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
8
8
0
0
0
% I
% Lys:
0
43
0
8
0
15
0
8
8
43
0
0
0
0
15
% K
% Leu:
8
15
0
0
65
0
0
0
0
0
50
36
8
8
8
% L
% Met:
8
0
36
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
0
8
0
8
0
% N
% Pro:
15
8
8
0
8
65
8
0
8
8
0
0
15
15
0
% P
% Gln:
0
0
0
65
8
0
15
0
8
0
8
22
0
8
0
% Q
% Arg:
0
15
0
0
0
0
0
0
0
22
8
8
0
8
0
% R
% Ser:
0
0
0
0
8
8
0
43
29
0
8
0
0
43
8
% S
% Thr:
8
0
0
0
0
0
0
8
0
0
8
0
8
0
36
% T
% Val:
8
8
22
8
0
0
0
22
0
22
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
15
0
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _