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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTR5 All Species: 14.24
Human Site: S389 Identified Species: 24.1
UniProt: Q9H9F9 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H9F9 NP_079131.3 607 68297 S389 L E V D V V D S K P E T P D L
Chimpanzee Pan troglodytes XP_001145158 607 68237 S389 L E V D V V D S K P E T P D L
Rhesus Macaque Macaca mulatta XP_001089026 607 68253 S389 L E V D V V D S K P E T P D L
Dog Lupus familis XP_534418 363 41163 L156 Y L Q R L L Q L K Y P G H L A
Cat Felis silvestris
Mouse Mus musculus Q80US4 605 67941 K390 E V D V V D S K P E T P D L E
Rat Rattus norvegicus NP_001102070 330 37120 S123 S F Q H L G V S S Q G C V D H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515798 283 31357 E76 D L E Q L G S E Q S L E D V E
Chicken Gallus gallus Q5ZJA4 611 69335 P393 V D I V D S K P E T P D L D P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998653 592 66401 S368 Y I H K L S L S L Q Q H R L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VEC3 648 75103 K377 K Q Q E R L N K M P K P P E G
Honey Bee Apis mellifera XP_623919 674 77387 W459 F G M R D E D W D V Y K V I N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784230 560 63388 S351 M Q E D S D G S Q K K S L K A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q940Z2 590 67861 T369 R E R M R L L T T A A F D R G
Baker's Yeast Sacchar. cerevisiae P53946 755 87542 A374 L E Q S L K K A Q M V E A E D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.5 56.6 N.A. 88.8 50.5 N.A. 34.9 78.7 N.A. 56.5 N.A. 28.8 41.5 N.A. 41.8
Protein Similarity: 100 100 99.1 58.6 N.A. 94 51.7 N.A. 40.8 86.5 N.A. 73.4 N.A. 49 59.5 N.A. 61.7
P-Site Identity: 100 100 100 6.6 N.A. 6.6 13.3 N.A. 0 6.6 N.A. 13.3 N.A. 13.3 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 20 N.A. 6.6 20 N.A. 13.3 33.3 N.A. 26.6 N.A. 53.3 13.3 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 20.5 25 N.A.
Protein Similarity: N.A. N.A. N.A. 38.2 42.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 8 8 0 8 0 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 8 8 8 29 15 15 29 0 8 0 0 8 22 36 8 % D
% Glu: 8 36 15 8 0 8 0 8 8 8 22 15 0 15 15 % E
% Phe: 8 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 8 0 0 0 15 8 0 0 0 8 8 0 0 15 % G
% His: 0 0 8 8 0 0 0 0 0 0 0 8 8 0 8 % H
% Ile: 0 8 8 0 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 8 0 0 8 0 8 15 15 29 8 15 8 0 8 0 % K
% Leu: 29 15 0 0 36 22 15 8 8 0 8 0 15 22 29 % L
% Met: 8 0 8 8 0 0 0 0 8 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 8 8 29 15 15 29 0 8 % P
% Gln: 0 15 29 8 0 0 8 0 22 15 8 0 0 0 0 % Q
% Arg: 8 0 8 15 15 0 0 0 0 0 0 0 8 8 0 % R
% Ser: 8 0 0 8 8 15 15 43 8 8 0 8 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 8 8 8 8 22 0 0 0 % T
% Val: 8 8 22 15 29 22 8 0 0 8 8 0 15 8 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 15 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _