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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTR5
All Species:
9.09
Human Site:
T420
Identified Species:
15.38
UniProt:
Q9H9F9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9F9
NP_079131.3
607
68297
T420
D
P
L
F
S
E
E
T
P
G
V
E
K
P
V
Chimpanzee
Pan troglodytes
XP_001145158
607
68237
T420
D
P
L
F
S
E
E
T
P
G
V
E
K
P
V
Rhesus Macaque
Macaca mulatta
XP_001089026
607
68253
T420
D
P
L
F
S
E
E
T
P
G
V
E
K
P
V
Dog
Lupus familis
XP_534418
363
41163
E187
V
A
E
D
Y
V
E
E
L
Q
K
W
R
C
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80US4
605
67941
P421
P
L
F
S
E
E
T
P
E
V
E
K
P
Q
V
Rat
Rattus norvegicus
NP_001102070
330
37120
E154
M
M
S
E
L
L
F
E
C
Y
R
I
P
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515798
283
31357
Q107
E
K
P
V
A
T
V
Q
P
V
F
N
L
A
E
Chicken
Gallus gallus
Q5ZJA4
611
69335
Q424
E
P
L
F
A
E
E
Q
P
E
A
E
K
P
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998653
592
66401
N399
L
E
A
E
L
N
E
N
E
E
P
G
K
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEC3
648
75103
R408
I
L
G
R
K
Q
A
R
Q
Q
Q
R
S
E
Q
Honey Bee
Apis mellifera
XP_623919
674
77387
H490
E
L
E
D
V
L
R
H
H
D
P
E
F
D
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784230
560
63388
K382
N
A
S
V
Q
R
S
K
Q
E
V
L
S
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q940Z2
590
67861
D400
K
L
M
S
K
D
N
D
D
D
D
E
Q
P
D
Baker's Yeast
Sacchar. cerevisiae
P53946
755
87542
E405
D
L
L
D
I
A
D
E
D
L
N
E
D
Q
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.5
56.6
N.A.
88.8
50.5
N.A.
34.9
78.7
N.A.
56.5
N.A.
28.8
41.5
N.A.
41.8
Protein Similarity:
100
100
99.1
58.6
N.A.
94
51.7
N.A.
40.8
86.5
N.A.
73.4
N.A.
49
59.5
N.A.
61.7
P-Site Identity:
100
100
100
6.6
N.A.
13.3
6.6
N.A.
6.6
66.6
N.A.
20
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
20
6.6
N.A.
20
80
N.A.
20
N.A.
6.6
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
25
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.2
42.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
8
0
15
8
8
0
0
0
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% C
% Asp:
29
0
0
22
0
8
8
8
15
15
8
0
8
8
8
% D
% Glu:
22
8
15
15
8
36
43
22
15
22
8
50
0
15
8
% E
% Phe:
0
0
8
29
0
0
8
0
0
0
8
0
8
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
22
0
8
0
0
8
% G
% His:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
0
0
0
0
0
0
8
0
0
8
% I
% Lys:
8
8
0
0
15
0
0
8
0
0
8
8
36
8
0
% K
% Leu:
8
36
36
0
15
15
0
0
8
8
0
8
8
0
8
% L
% Met:
8
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
8
8
8
0
0
8
8
0
0
0
% N
% Pro:
8
29
8
0
0
0
0
8
36
0
15
0
15
43
8
% P
% Gln:
0
0
0
0
8
8
0
15
15
15
8
0
8
15
8
% Q
% Arg:
0
0
0
8
0
8
8
8
0
0
8
8
8
0
0
% R
% Ser:
0
0
15
15
22
0
8
0
0
0
0
0
15
0
8
% S
% Thr:
0
0
0
0
0
8
8
22
0
0
0
0
0
0
0
% T
% Val:
8
0
0
15
8
8
8
0
0
15
29
0
0
0
43
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _