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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTR5
All Species:
29.39
Human Site:
Y221
Identified Species:
49.74
UniProt:
Q9H9F9
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9F9
NP_079131.3
607
68297
Y221
G
G
S
Q
A
A
G
Y
L
Q
R
L
L
Q
L
Chimpanzee
Pan troglodytes
XP_001145158
607
68237
Y221
G
G
S
Q
A
A
G
Y
L
Q
R
L
L
Q
L
Rhesus Macaque
Macaca mulatta
XP_001089026
607
68253
Y221
G
G
S
Q
A
A
G
Y
L
Q
R
L
L
Q
L
Dog
Lupus familis
XP_534418
363
41163
A29
L
Q
F
R
A
V
C
A
R
G
R
G
G
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80US4
605
67941
Y221
G
G
S
Q
A
A
G
Y
L
Q
R
L
L
Q
L
Rat
Rattus norvegicus
NP_001102070
330
37120
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515798
283
31357
Chicken
Gallus gallus
Q5ZJA4
611
69335
Y223
G
G
C
Q
A
A
V
Y
L
Q
R
L
L
Q
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998653
592
66401
Y222
G
G
G
Q
A
A
A
Y
Y
Q
R
L
L
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEC3
648
75103
Y207
G
G
Y
H
I
I
T
Y
L
F
R
L
M
Q
M
Honey Bee
Apis mellifera
XP_623919
674
77387
Y211
G
G
Y
H
I
T
S
Y
M
H
R
L
L
Q
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784230
560
63388
I224
A
H
C
R
R
L
N
I
G
G
T
H
L
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q940Z2
590
67861
A210
F
L
S
D
T
G
Y
A
S
R
Q
E
L
E
S
Baker's Yeast
Sacchar. cerevisiae
P53946
755
87542
Y222
G
G
H
Q
A
V
D
Y
L
N
D
L
M
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.5
56.6
N.A.
88.8
50.5
N.A.
34.9
78.7
N.A.
56.5
N.A.
28.8
41.5
N.A.
41.8
Protein Similarity:
100
100
99.1
58.6
N.A.
94
51.7
N.A.
40.8
86.5
N.A.
73.4
N.A.
49
59.5
N.A.
61.7
P-Site Identity:
100
100
100
13.3
N.A.
100
0
N.A.
0
86.6
N.A.
80
N.A.
46.6
53.3
N.A.
6.6
P-Site Similarity:
100
100
100
20
N.A.
100
0
N.A.
0
86.6
N.A.
80
N.A.
60
60
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
25
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.2
42.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
58
43
8
15
0
0
0
0
0
15
0
% A
% Cys:
0
0
15
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% E
% Phe:
8
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
65
65
8
0
0
8
29
0
8
15
0
8
8
0
8
% G
% His:
0
8
8
15
0
0
0
0
0
8
0
8
0
0
0
% H
% Ile:
0
0
0
0
15
8
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
8
0
0
0
8
0
0
50
0
0
65
65
0
58
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
15
0
8
% M
% Asn:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
50
0
0
0
0
0
43
8
0
0
58
0
% Q
% Arg:
0
0
0
15
8
0
0
0
8
8
65
0
0
0
8
% R
% Ser:
0
0
36
0
0
0
8
0
8
0
0
0
0
0
8
% S
% Thr:
0
0
0
0
8
8
8
0
0
0
8
0
0
8
0
% T
% Val:
0
0
0
0
0
15
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
15
0
0
0
8
65
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _