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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF2C3
All Species:
31.82
Human Site:
S586
Identified Species:
58.33
UniProt:
Q9H9G7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9G7
NP_079128.2
860
97360
S586
L
V
P
H
Q
R
P
S
V
F
Q
Q
P
V
I
Chimpanzee
Pan troglodytes
XP_524664
845
95948
S571
L
V
P
H
Q
R
P
S
V
F
Q
Q
P
V
I
Rhesus Macaque
Macaca mulatta
XP_001100725
1053
117937
P779
L
L
P
Q
G
R
P
P
V
F
Q
Q
P
V
I
Dog
Lupus familis
XP_532562
881
100044
S602
L
V
P
H
Q
R
P
S
V
F
Q
Q
P
V
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8CJF9
860
97222
S586
L
V
P
H
Q
R
P
S
V
F
Q
Q
P
V
I
Rat
Rattus norvegicus
Q9QZ81
860
97300
P586
L
L
P
Q
G
R
P
P
V
F
Q
Q
P
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510243
1052
118200
S778
L
V
P
H
Q
R
P
S
V
F
Q
Q
P
V
I
Chicken
Gallus gallus
Q5ZLG4
860
97253
S586
L
V
P
H
Q
R
P
S
V
F
Q
Q
P
V
I
Frog
Xenopus laevis
Q4KLV6
884
99519
S600
L
V
P
H
Q
R
P
S
V
F
Q
Q
P
V
I
Zebra Danio
Brachydanio rerio
A3KPK0
860
97313
S586
L
V
P
H
Q
R
P
S
V
F
Q
Q
P
V
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUQ5
1214
136831
N944
N
S
K
L
N
G
I
N
H
K
I
K
D
D
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34681
1040
115397
V733
K
I
T
N
K
Y
L
V
D
Q
P
T
M
V
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04379
1048
116172
L748
A
L
S
R
R
I
P
L
V
S
D
R
P
T
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
62.2
97.1
N.A.
98.7
80.2
N.A.
81.4
99
80.1
95.1
N.A.
22.9
N.A.
32.3
N.A.
Protein Similarity:
100
98.2
71.9
97.3
N.A.
99
89.7
N.A.
81.5
99.1
88.3
97.7
N.A.
36.4
N.A.
50
N.A.
P-Site Identity:
100
100
73.3
100
N.A.
100
73.3
N.A.
100
100
100
100
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
100
80
100
N.A.
100
80
N.A.
100
100
100
100
N.A.
13.3
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
8
0
8
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
77
0
0
0
0
0
% F
% Gly:
0
0
0
0
16
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
62
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
8
8
0
0
0
8
0
0
0
85
% I
% Lys:
8
0
8
0
8
0
0
0
0
8
0
8
0
0
0
% K
% Leu:
77
24
0
8
0
0
8
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
0
0
8
8
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
77
0
0
0
85
16
0
0
8
0
85
0
8
% P
% Gln:
0
0
0
16
62
0
0
0
0
8
77
77
0
0
0
% Q
% Arg:
0
0
0
8
8
77
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
8
8
0
0
0
0
62
0
8
0
0
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
8
0
8
0
% T
% Val:
0
62
0
0
0
0
0
8
85
0
0
0
0
85
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _